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Pathological Spectrum of Melanoma: A Nine-Year Retrospective Analysis of Tumor Characteristics Across Diverse Anatomic Sites.
Cureus
December 2024
Ophthalmology, All India Institute of Medical Sciences, Madurai, Madurai, IND.
Melanoma is a highly aggressive malignancy originating from melanocytes, characterized by its potential to arise in various anatomic locations, both common and rare. The incidence of melanoma has been steadily increasing globally, with variations in clinical presentation, tumor behavior, and prognosis depending on the anatomical site involved. Understanding the diverse pathological spectrum of melanoma is critical for optimizing diagnostic and therapeutic strategies.
View Article and Find Full Text PDFA Rare Case of Malignant Melanoma of the Glans Penis in a Young Male Treated with an Organ-Preserving Surgical Procedure.
Cureus
October 2024
Urology, SRM Medical College Hospital and Research Centre, Chennai, IND.
Penile melanoma is a rare and highly invasive cancer that is generally diagnosed in the sixth to seventh decades of life. We report a rare case of primary malignant melanoma of the glans penis in a 38-year-old man who presented with a proliferative lesion over the glans with discoloration for six months. The clinical and metastatic workups were unremarkable.
View Article and Find Full Text PDFClinicopathological and Molecular Features of Penile Melanoma With a Proposed Staging System.
Am J Surg Pathol
July 2024
Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA.
Penile melanomas (PM) are an exceedingly rare subtype of mucosal melanoma (MM), and we reviewed the clinicopathologic features and molecular profile in 8 PMs. The patient ages ranged from 46 to 78 (mean: 62.8) years with involvement on the glans (n=5; 62.
View Article and Find Full Text PDFConfocal Assessment of Pigmented-Mucosal Lesions: A Monocentric, Retrospective Evaluation of Lip and Genital Area.
Dermatol Pract Concept
January 2024
UOC di Dermatologia, Dipartimento di Scienze Mediche e Chirurgiche, Fondazione Policlinico Universitario A. Gemelli - IRCCS, Rome, Italy.
Introduction: Pigmentation of lip and/or genitalia is mainly due to the development of benign melanotic macules, with a less occurrence of melanocytic and other non-melanocytic lesions. Mucosal melanoma has worse prognosis compared with cutaneous counterpart, hence identification of atypical features for an early diagnosis is crucial.
Objectives: The aim of this study was to report further data of confocal features characterizing pigmented mucosal lesions of genital area and of the lips and test the diagnostic role of the reflectance confocal microscopy (RCM)lip score.
Penile melanoma diagnosis aided by in vivo confocal microscopy.
JAAD Case Rep
February 2024
University Hospital Galway, National University of Ireland Galway.
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