AI Article Synopsis
- A study monitored 17 HIV-infected patients with untreated subclinical visceral leishmaniasis (VL) over time.
- None of the 11 patients on highly active antiretroviral therapy (HAART) developed symptomatic VL, while 2 out of 6 patients on other treatments did.
- The results indicate that HAART may prevent the progression of latent VL into symptomatic disease.
Article Abstract
Seventeen human immunodeficiency virus-infected patients who were harboring untreated subclinical visceral leishmaniasis (VL) were prospectively followed up. None of the 11 patients who received highly active antiretroviral therapy (HAART) presented with symptomatic VL during follow-up, whereas 2 out of 6 patients who received therapy other than HAART had an episode of overt kala-azar. These findings suggest that HAART does not induce the evolution of latent VL into symptomatic disease.
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| http://dx.doi.org/10.1086/318708 | DOI Listing |
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