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Impella 5.5 as a bridge-to-surgery in acute ischemic mitral regurgitation post-percutaneous coronary intervention: a case report.

J Cardiothorac Surg

November 2024

Division of Advanced Heart Failure and Cardiac Transplant, University of South Florida, Tampa General Hospital, 7110 S Trask Street, Tampa, FL, 33616, USA.

Article Synopsis
  • Acute ischemic mitral regurgitation (AIMR) is a serious condition that can occur during acute coronary syndrome, leading to rapid heart failure and shock; intra-aortic balloon pumps (IABP) are often used to stabilize patients before surgery.
  • A 74-year-old man with cardiac issues underwent an initial stenting procedure but continued to experience severe hypoxia and hypotension, prompting the upgrade to an Impella device for better circulatory support.
  • Although his condition improved enough for surgery to replace the mitral valve and perform bypass grafting, he later developed bacterial pneumonia and acute respiratory distress syndrome, leading to his death shortly after.
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Article Synopsis
  • Fabry Disease cardiomyopathy (FDc) and sarcomeric hypertrophic cardiomyopathy (HCM) show similar hypertrophic heart features, particularly anomalies of the mitral valve apparatus (AMVA), which were assessed in this study for better diagnosis and understanding of disease progression.
  • The study involved 80 Fabry patients and 40 HCM patients, utilizing cardiovascular magnetic resonance (CMR) imaging to measure various AMVA and compare groups with similar levels of left ventricular hypertrophy.
  • Results indicated that Fabry patients exhibited greater hypertrophy of papillary muscles compared to HCM patients, alongside significant anomalies like apical displacement, supporting the idea that AMVA may serve as early indicators in Fabry disease. *
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Non-ischemic papillary muscle rupture (PMR) is rare. PMR caused by myocarditis in the presence of concurrent infective endocarditis (IE) and myocardial infarction (MI) has not been described. We report a 46-year-old male with recurrent MRSA bacteremia who presented in septic shock and suffered cardiac arrest.

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Background: The prognosis of hypertrophic cardiomyopathy (HCM) varies from mild disease with a normal life expectancy to heart failure and sudden cardiac death (SCD). The identification of patients who are at high risk for SCD remains challenging.

Aims: In this study, we evaluated the prognostic value of papillary muscle-free strain in HCM patients.

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Background: Papillary muscle (PM) infarction (PMI) detected by cardiac magnetic resonance imaging (CMR) is associated with poor outcomes. Whether PM parameters provide more value for mitral regurgitation (MR) management currently remains unclear. Therefore, we examined the prognostic value of PMI using CMR in patients with MR.

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