AI Article Synopsis
- Helicobacter pylori (HP) is commonly linked to chronic active gastritis and peptic ulcers, but its specific mechanisms of causing these conditions remain unclear.
- A significant increase in eosinophils was observed in the gastric mucosa of HP-infected patients compared to those with HP-negative gastritis, despite similar levels of mast cells.
- Further research is needed to understand the source and role of eosinophilia in HP infections, its connection to disease progression, and the relationship between eosinophils and mast cells.
Article Abstract
Although Helicobacter pylori (HP) is frequently associated with chronic active gastritis and peptic ulcers, its exact pathogenic role or the pathomechanism is still unclear. Here, we describe a striking, statistically significant increase of eosinophils in HP infected gastric mucosa compared to HP negative gastritis with similar activity. In both cases, the mean number of the mast cells in the mucosa was comparable, although the individual values showed wide distribution. The source and role of eosinophilia in HP infected mucosa, the potential link between the degree of eosinophilia and the clinical progression, as well as between eosinophils and mast cells require further study.
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| http://dx.doi.org/10.1007/BF02904816 | DOI Listing |
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