AI Article Synopsis
- - The study aimed to identify risk factors for migraine with aura (MA) by analyzing pairs of twins who do not have the same migraine history (discordant pairs).
- - It involved 5,360 same-gender twin pairs; after screening, they found that environmental factors explained about 50% of what contributes to becoming susceptible to MA.
- - Key factors like education, marital status, and substance use showed no links to MA, but stress and bright light were found to trigger MA attacks in 44% and 28% of the twins, respectively.
Article Abstract
The aim of the present study was to detect possible risk factors in migraine with aura (MA) by analysis of discordant twin-pairs. In a recent population-based twin study we established that environmental factors account for approximately 50% of the variation in liability to MA. A cohort of 5,360 same-gender twin-pairs from the general population was screened for migraine. All twin-pairs with possible migraine were interviewed by a physician. A questionnaire provided information about living conditions and lifestyle. Of the 169 discordant twin-pairs 51 were monozygotic and 118 were dizygotic twin-pairs. Several putative risk factors-schooling, education, marital status, smoking status and alcohol consumption-showed no association with MA. The presence of migraine without aura or tension-type headache did not increase the risk of MA. Stress and mental tension, and bright light precipitated attacks of MA in, respectively, 44% and 28% of the twins.
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| http://dx.doi.org/10.1046/j.1468-2982.2000.00135.x | DOI Listing |
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