Objective: We describe four cases of osteomyelitis that occurred in and around foci of preexisting osteonecrosis in the medullary cavity. Although sequestration is a well-known complication of osteomyelitis, there is little information known about infection occurring in proximity to large regions of already necrotic bone.
Conclusion: Osteomyelitis and bone infarction can be seen in the same patient population. Medullary infarcts may function as sequestra, predisposing patients to osteomyelitis and soft-tissue infection.
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