Objective: To investigate if complete resolution of endometriosis by laparoscopic surgery is beneficial to postoperative fecundity, dysmenorrhea and dyspareunia.
Design: An observational comparative study on the outcome of laparoscopic surgery.
Patients: Laparoscopically-treated symptomatic women with endometriosis (total n = 236); complete (n = 185) and incomplete (n = 51) surgery groups.
Measurements: Postoperative fecundity and symptom reduction.
Results: With whole populations, no surgical completeness-related difference was observed in cumulative pregnancy rates during the postoperative days 0-400 (cycle fecundity rate = 0.0319). Further accumulation of pregnant cases was followed in the complete surgery group (final cumulative pregnancy rate = 80%), but not in the counterpart group (p = 0.003). The similar result was obtained when only r-AFS classification stages III and IV were compared (p = 0.007). No r-AFS stage-related difference was observed in cumulative pregnancy rates when only patients of complete surgery were selected for comparison. The surgery reduced dysmenorrhea (84.7%) and dyspareunia (80.0%).
Conclusions: Laparoscopic conservative surgery for endometriosis, especially when it is complete, increases fecundity and reduces disease-related symptoms, such as dysmenorrhea and dyspareunia.
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http://dx.doi.org/10.1111/j.1447-0756.2000.tb01350.x | DOI Listing |
Environ Res
January 2025
School of Public Health, Nanjing Medical University, Nanjing, China; Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, China. Electronic address:
Background: Exposure to suboptimal temperatures during pregnancy has been associated with adverse pregnancy and birth outcomes related to placental development disorders. No prior studies have examined the potential impacts of temperature on placental markers. We conducted an investigation into the cumulative impact of daily ambient temperature on critical clinical placental perfusion and function markers during the placentation period, utilizing data from a prospective birth cohort in Nanjing, China.
View Article and Find Full Text PDFBiomedicines
December 2024
CCRM Genetics, 10290 Ridgegate Circle, Lone Tree, CO 80124, USA.
Abnormally fertilized embryos are often discarded during in vitro fertilization due to the fact that known chromosomal ploidy abnormalities lead to implantation failure or pregnancy loss. The objective of this study was to determine if pronuclear numeration (PN) observed at fertilization check is representative of the true ploidy status of the subsequent developing blastocyst in order to maximize the number of viable embryos available for infertility patients and increase their chances of conception. Upon successful fertilization, pronuclear numeration was noted, and zygotes were cultured to the blastocyst stage.
View Article and Find Full Text PDFClin Pharmacol Ther
January 2025
School of Pharmacy, Sungkyunkwan University, Suwon, South Korea.
Immunization rates of maternal influenza vaccination during pregnancy remain suboptimal, with concerns about potential harm to the mothers and their offspring. We conducted a population-based cohort study, using mother-child linked database in Korea: (a) maternal cohort between December 2019, and March 2022; (b) neonatal cohort between September 2020, and June 2021. Exposure was defined as influenza vaccination during pregnancy.
View Article and Find Full Text PDFVet Sci
January 2025
Institute of Biodiversity and Forests-IBEF, Federal University of Western Pará (UFOPA), Santarem 68040-255, PA, Brazil.
We aimed to evaluate the reproductive efficiency of Nelore cows in fixed-time artificial insemination (FTAI) programs with early resynchronization. A total of 468 Nelore cows were divided into two experimental groups: R30-conventional resynchronization at 30 days ( = 234); R22-early resynchronization at 22 days ( = 234). Both groups followed a synchronization protocol using intravaginal progesterone devices combined with the administration of steroids and gonadotropins.
View Article and Find Full Text PDFAm J Public Health
January 2025
Stacey L. Rowe is with the School of Nursing and Health Professions, University of San Francisco, San Francisco, CA. Sheena G. Sullivan is with the School of Clinical Sciences, Monash University, Melbourne, Australia. Flor M. Munoz is with the Department of Pediatrics, Baylor College of Medicine, Houston, TX. Matthew M. Coates and Onyebuchi A. Arah are with the Department of Epidemiology, Fielding School of Public Health, University of California, Los Angeles. Annette K. Regan is with the Department of Research and Evaluation, Kaiser Permanente Research, Pasadena, CA.
To estimate maternal COVID-19, influenza, and pertussis vaccine uptake during pregnancy by insurance type and identify factors characterizing those vaccinated and unvaccinated. We conducted a US cohort study of pregnant individuals (for pregnancies ending December 11, 2020-September 30, 2022) using insurance claims data. We calculated vaccination probability using Kaplan-Meier methods and identified factors associated with vaccination through binomial regression with inverse probability weights.
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