Case Report: A 63 year-old man with a six month history of a red-orange lesion located in the caruncle of his right eye is presented. Surgical excision was then performed, and the histological diagnosis of oncocytoma was established.
Discussion: The oncocytoma is an uncommon, relatively benign tumor, composed of transformed epithelial cells of the ducts. The histogenetic characteristics and prognosis are briefly discussed.
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Oncocytoma: a rare neoplasm of the caruncle.
BMJ Case Rep
January 2025
Ophthalmology, Madigan Army Medical Center, Tacoma, Washington, USA.
Oncocytoma is a rare benign neoplasm of the glandular tissue, most commonly found in the caruncle of the eye. These lesions have an excellent prognosis and have not been reported to recur after resection from the caruncle. Given the wide range of differentials and potential for malignancy, excision and histopathological examination are recommended to establish the diagnosis and guide proper treatment.
View Article and Find Full Text PDFOncocytic Carcinoma Ex-Pleomorphic Adenoma of the Lacrimal Gland.
Ophthalmic Plast Reconstr Surg
January 2025
Adnexal Service, Moorfields Eye Hospital, London EC1V 2PD, United Kingdom.
Oncocytic carcinoma is a rare malignant neoplasm of oncocytic cells, such cells being characterized by abundant granular eosinophilic cytoplasm, invasive growth, and pronounced cellular pleomorphism. It may arise de novo, or through malignant transformation of a pre-existing benign oncocytoma. Oncocytic carcinoma most commonly occurs in the salivary glands, with rare involvement of the ocular adnexa where it mainly affects caruncle, conjunctiva, and lacrimal sac, and only very arises in the lacrimal gland.
View Article and Find Full Text PDFClinical and histopathological profile of primary caruncular lesions.
Indian J Ophthalmol
June 2022
Department of Ocular Pathology, Larson and Tourbo, Vision Research Foundation, Chennai, Tamil Nadu, India.
Purpose: To provide a retrospective analysis of lesions of the caruncle which have been very rarely reported in the literature.
Methods: A retrospective review of all the caruncular lesions between January 2000 and January 2020 was done at a single tertiary eye care hospital. The lesions were classified as benign and malignant lesions.
Oncocytic lesions of the ocular adnexa: A review of the histopathology with a brief discussion of the pathogenesis.
Saudi J Ophthalmol
April 2022
Eye Associates of New Mexico, Albuquerque, NM, USA.
Oncocytic lesions may be metaplastic, hyperplastic, or neoplastic and occur in a variety of tissues, including those of the ocular adnexa. Oncocytes are enlarged epithelial cells with abundant eosinophilic granules in the cytoplasm, which represent large mitochondria with distorted cristae. The causes of oncocytic lesions remain uncertain, although in some sites such as the lacrimal sac, chronic inflammation may be a factor.
View Article and Find Full Text PDFClinico-pathological correlation of lacrimal caruncle tumors: a retrospective analysis over 22 years at the University Eye Hospital Bonn.
Graefes Arch Clin Exp Ophthalmol
April 2022
Department of Ophthalmology, University Hospital Bonn, Ernst-Abbe-Str. 2, 53127, Bonn, Germany.
Purpose: The lacrimal caruncle is composed of numerous structures including different glands as well as hair follicles. Accordingly, the spectrum of benign and malignant lesions is broad, and the clinical diagnosis is often challenging. Here we systematically analyzed excised caruncular tumors over the past 22 years with special emphasis on the clinico-pathological correlation to provide a guidance for clinicians.
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