Case Report: Cellular neurothekeoma is a distinctive subtype of neurothekeoma with an undetermined histopathogenesis. We report a very rare case of bulbar conjunctiva cellular neurothekeoma in a 23-year-old woman.
Discussion: Neurothekeoma or nerve sheath myxoma is a rare benign tumor, which arises during childhood, and early adult life. It mainly locates in the upper portion of the body (head, neck and upper limbs). As far as we know, this is the first case report of cellular neurothekeoma in this location. Excisional biopsy is necessary to make the differential diagnosis from other cystic and malignant pathologies of the conjunctiva.
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J Clin Pathol
January 2025
Department of Pathology, Ghent University Hospital, Ghent University, Ghent, Belgium
Diagn Pathol
November 2024
Sistema Nacional de Investigación, Secretaria Nacional de Ciencia, Tecnología e Innovación, Panama City, Panama.
Atypical cellular neurothekeoma is a rare benign soft-tissue tumour that usually arises in the head and neck region, shoulder girdles, and proximal extremities, predominantly in young women. This dermal neoplasm is under-reported in the literature and is not uncommonly misdiagnosed as a malignant tumour due to its worrisome histologic characteristics. Currently, the diagnosis of cellular neurothekeoma relies on a panel of non-specific immunohistochemical markers and its etiopathogenesis is unknown.
View Article and Find Full Text PDFJAAD Case Rep
November 2024
Sagis Diagnostics, Houston, Texas.
Dermatol Pract Concept
July 2024
Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
J Cutan Pathol
December 2024
Department of Oral Diagnosis, Piracicaba Dental School, University of Campinas, Piracicaba, Brazil.
Cellular neurothekeoma (CN) is a benign dermal neoplasm that most often affects the head and neck region and rarely occurs in the oral mucosa. We report a rare case of CN with atypical features on the floor of the mouth and summarize the reported cases of oral CN in English-language literature. A 62-year-old woman presented with a 6-month history of a painless mass on the floor of the mouth.
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