Background: Movements and vibrations of intraocular structures can be observed during vitrectomy with mechanical cutting systems. We experimentally compared these intraocular motion artifacts between mechanical and erbium:YAG laser vitrectomy.
Material And Methods: The intraocular structures were reliably simulated by a 0.9-mm-wide foil (thickness 10 microns) in a water-filled cuvette. The movements caused by commercial mechanical cutter systems were compared with vibration induced by means of laser surgery probes (laser pulse energy 20 mJ). Laser triangulation was used to measure the movement amplitudes at various cutting rates of 2, 5, and 10 Hz and a constant suction force of 50 mmHg.
Results: At all cutting rates the amplitude with the laser was less than that with the mechanical system. The ratio of the maximal amplitude between laser surgery probes (AL) and mechanical cutter system (AM) was AL/AM = 0.29 at 10 Hz, AL/AM = 0.33 at 5 Hz, and AL/AM = 0.45 at 2 Hz.
Conclusion: The reduced intraocular movements with erbium:YAG laser vitrectomy constitutes a potential advantage for the nonpulsatile vitrectomy.
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http://dx.doi.org/10.1007/s003470070048 | DOI Listing |
Heliyon
November 2024
Department of Cataract, Shanxi Eye Hospital Affiliated to Shanxi Medical University, Taiyuan, Shanxi, PR China.
Purpose Of The Review: In recent years, Berger's space (BS), the potential space between the posterior lens capsule and the anterior hyaloid membrane, has received little attention from the ophthalmic clinical community. This is primarily due to the limited documentation, with only a few isolated case reports detailing foreign bodies in this area.
Recent Findings: Recent advances in medical imaging technology have enabled the visualization of the BS under various circumstances.
Sci Rep
January 2025
Ophthalmic Pathology Laboratory, L V Prasad Eye Institute, Kallam Anji Reddy Campus, 500034, Hyderabad, India.
To examine ultrastructural changes in the trabecular meshwork (TM) in patients with primary and secondary glaucoma using scanning electron microscopy (SEM). This was a qualitative descriptive hospital-based study on the ultrastructure of the TM. Pure TM samples were collected after microincisional trabeculectomy from 26 patients with primary or secondary glaucoma and 10 control samples from eye bank donor corneas.
View Article and Find Full Text PDFTurk J Ophthalmol
December 2024
Kastamonu Training and Research Hospital, Clinic of Ophthalmology, Kastamonu, Türkiye.
We present the case of a patient who came to the emergency department with a significant decrease in vision and dilated pupil in the left eye. Since neurological pathologies were primarily considered, diffusion brain magnetic resonance imaging (MRI) and brain computed tomography (CT) were requested. After the results were reported as normal, we were consulted.
View Article and Find Full Text PDFNat Commun
December 2024
Department of Ophthalmology, Columbia University, New York, NY, USA.
Best1 and Best2 are two members of the bestrophin family of anion channels critically involved in the prevention of retinal degeneration and maintenance of intraocular pressure, respectively. Here, we solved glutamate- and γ-aminobutyric acid (GABA)-bound Best2 structures, which delineate an intracellular glutamate binding site and an extracellular GABA binding site on Best2, respectively, identified extracellular GABA as a permeable activator of Best2, and elucidated the co-regulation of Best2 by glutamate, GABA and glutamine synthetase in vivo. We further identified multiple small molecules as activators of the bestrophin channels.
View Article and Find Full Text PDFFront Biosci (Landmark Ed)
December 2024
Halberg Chronobiology Center, University of Minnesota, Minneapolis, MN 55455, USA.
This review explores the intricate relationship between glaucoma and circadian rhythm disturbances. As a principal organ for photic signal reception and transduction, the eye plays a pivotal role in coordinating the body's circadian rhythms through specialized retinal ganglion cells (RGCs), particularly intrinsically photosensitive RGCs (ipRGCs). These cells are critical in transmitting light signals to the suprachiasmatic nucleus (SCN), the central circadian clock that synchronizes physiological processes to the 24-hour light-dark cycle.
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