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Unraveling the origins of PGY-sRNA-6, BZL-sRNA-20, and XKC-sRNA-h3.
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Markey Cancer Center, University of Kentucky, Lexington, KY, USA.
Purpose: Patients with partial or complete DPD deficiency have decreased capacity to degrade fluorouracil and are at risk of developing toxicity, which can be even life-threatening.
Case: A 43-year-old man with moderately differentiated rectal adenocarcinoma on capecitabine presented to the emergency department with complaints of nausea, vomiting, diarrhea, weakness, and lower abdominal pain for several days. Laboratory findings include grade 4 neutropenia (ANC 10) and thrombocytopenia (platelets 36,000).
Authors' Reply "Effect of Adiposity Status on Salivary Streptococcus mutans and Streptococcus sobrinus." Oral Diseases. Advance Online Publication. https://doi.org/10.1111/odi.15111.
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Microbial traits are critical for carbon sequestration and degradation in terrestrial ecosystems. Yet, our understanding of the relationship between carbon metabolic strategies and genomic traits like genome size remains limited. To address this knowledge gap, we conducted a global-scale meta-analysis of 2650 genomes, integrated whole-genome sequencing data, and performed a continental-scale metagenomic field study.
View Article and Find Full Text PDFAdditive Effects of Multiple Global Change Factors on Plant Invasions Are Common.
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Department of Biology, University of Konstanz, Konstanz, Germany.
Quantifying how co-acting global change factors (GCFs) influence plant invasion is crucial for predicting future invasion dynamics. We did a meta-analysis to assess pairwise effects of five GCFs (elevated CO, drought, eutrophication, increased rainfall and warming) on native and alien plants. We found that alien plants, compared to native plants, suffered less or benefited more for four of the eight pairwise GCF combinations, and that all GCFs acted additively.
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