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Neurosarcoidosis in a 67-Year-Old Male Without Pulmonary Involvement: A Case Report.
Cureus
September 2024
Internal Medicine, Ittefaq Hospital, Lahore, PAK.
Article Synopsis
- Neurosarcoidosis is a rare form of sarcoidosis that complicates the nervous system, making it challenging to diagnose and treat due to its diverse symptoms.
- A case of a 67-year-old man showed signs like altered sensorium and weight loss, leading to tests that eventually diagnosed him with neurosarcoidosis based on imaging and biopsy results.
- Treatment with prednisolone and methotrexate resulted in significant improvement, illustrating the need for a multidisciplinary approach in handling such complex cases.
Gastrointestinal Manifestations of Sarcoidosis: A State-of-the-Art, Comprehensive Review of the Literature-Practical Clinical Insights and Many Unmet Needs on Diagnosis and Treatment.
Pharmaceuticals (Basel)
August 2024
Pulmonology Unit, Department of Medical Surgical and Health Sciences, University of Trieste, 34149 Trieste, Italy.
Article Synopsis
- This literature review examines the role of the gastrointestinal (GI) tract in sarcoidosis, which is a rare inflammatory disease that can be difficult to diagnose and treat due to overlapping symptoms with other GI disorders.* -
- GI sarcoidosis can impact any area of the gastrointestinal system, particularly the stomach and small intestine, leading to symptoms that range from mild discomfort to serious complications like obstruction or perforation.* -
- Current treatment options primarily involve corticosteroids, but their long-term effectiveness and safety are questionable, highlighting the urgent need for better diagnostic methods and standardized treatment protocols.*
Symptomatic hypercalcemia and lytic lesions of the skull revealing sarcoidosis: A case report.
Radiol Case Rep
December 2024
Department of Internal Medicine, Mohamed Tahar Maamouri University Hospital, Nabeul, Tunisia.
Sarcoidosis is a systemic granulomatosis of unknown etiology. Mediastinal lymph node and pulmonary involvement are the most characteristic manifestations. However, bone involvement is rare during sarcoidosis.
View Article and Find Full Text PDFSarcoidosis presenting as isolated massive splenomegaly: A case report.
Clin Case Rep
August 2024
Department of General Surgery Saint George Hospital University Medical Center, Saint George University of Beirut Beirut Lebanon.
Key Clinical Message: Sarcoidosis is a systemic granulomatous disease with an unknown cause, marked by the presence of noncaseating granulomas in the affected organs. While the pulmonary interstitium is most frequently involved, the disease can affect almost any other organ system. Extrapulmonary involvement can occur with or without lung involvement, but isolated extrapulmonary involvement is a rare event.
View Article and Find Full Text PDFAn Atypical Case of Extrapulmonary Sarcoidosis with Severe Hypercalcemia as Initial Presentation, Successfully Treated with Glucocorticoids.
Clin Pract
June 2024
Department of Pathology, University of Missouri, Columbia, MO 65212, USA.
Background: Sarcoidosis is a multisystemic disease that is histologically characterized by non-caseating granulomas in one or more organs. Although hypercalcemia is commonly seen in sarcoidosis, clinically significant hypercalcemia as the initial presentation of sarcoidosis is exceedingly rare. Long-standing hypercalcemia can lead to several complications and needs to be adequately managed to prevent irreversible damage.
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