Effect of subthalamic nucleus stimulation on levodopa-induced dyskinesia in Parkinson's disease.

Neurology

Department of Clinical and Biological Neurosciences, University Hospital of Grenoble, and INSERM U318, Joseph Fourier University, France.

Published: December 2000

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Article Abstract

Article abstract-The authors studied the effect of bilateral subthalamic nucleus stimulation on levodopa-induced dyskinesias in 24 consecutive parkinsonian patients with disabling dyskinesias. The improvement in the three subtypes of levodopa-induced dyskinesias was significant from the third postoperative month and was mainly due to the decrease in the daily dose of levodopa allowed by the stimulation-induced improvement in the motor score.

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http://dx.doi.org/10.1212/wnl.55.12.1921DOI Listing

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