This paper was presented in place of one that was to have been given by the late Professor A.G. Khomenko, Director of the Central Tuberculosis Research Institute, Moscow. Professor Khomenko had a long and distinguished career and with his death Russia has lost one of its finest and most active workers in the fight against TB.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1177/00369330000450S106 | DOI Listing |
RSC Med Chem
December 2024
Department of Medicinal Chemistry, N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry 9, Akademika Lavrentieva Ave. 630090 Novosibirsk Russia
Respiratory syncytial virus (RSV) is the leading cause of acute lower respiratory infections in babies across the world. Irrespective of progress in the development of RSV vaccines, effective small molecule drugs are still not available on the market. Based on our previous data we designed and synthesized triazole-linked coumarin-monoterpene hybrids and showed that they are indeed effective in inhibiting the RSV replication.
View Article and Find Full Text PDFMolecules
December 2021
Department of Medicinal Chemistry, N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Acad. Lavrentjev Ave. 9, 630090 Novosibirsk, Russia.
Respiratory syncytial virus (RSV) is a critical cause of infant mortality. However, there are no vaccines and adequate drugs for its treatment. We showed, for the first time, that O-linked coumarin-monoterpene conjugates are effective RSV inhibitors.
View Article and Find Full Text PDFScott Med J
October 2000
Medical Emergency Relief International (MERLIN), Moscow.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!