The nociceptive flexion reflex (NFR) of the lower limbs (RIII reflex) was examined bilaterally in 54 cluster headache (CH) patients suffering from episodic CH (ECH) and chronic CH (CCH). Fifteen ECH patients were examined in both remission and active phases. The RIII reflex threshold (Tr) and the threshold of pain sensation (Tp) were significantly reduced on the symptomatic side in patients with episodic CH during the bout. During the active phase of episodic CH an inverse correlation was found between the severity of CH (ratio: number of cluster periods/years of illness duration) and the Tp, which may suggest a role for secondary central sensitization in pain pathways. The lower Tr and Tp on the symptomatic side is in keeping with previous observations exploring pain mechanisms using different methods (i.e. corneal reflex, pain pressure threshold). On the whole, these data tie in with the view of an impairment of the pain control system, which parallels the periodicity of the disorder in the episodic form.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/j.1468-2982.2000.00096.x | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Reduction of lower limb spasticity after the suppression of intravesical noxious stimulus documented by gait analysis.
J Spinal Cord Med
November 2024
Service de Médecine Physique et Réadaptation, Hôpital Henry-Gabrielle, Hospices Civils de Lyon, Saint-Genis-Laval, France.
Article Synopsis
- Spasticity is linked to increased muscle tension and hyperactive spinal reflexes, and noxious stimuli like bladder stones can amplify this condition after spinal cord injury.
- A case study showed that after removing a bladder stone, a male subject experienced improved gait kinematics, such as reduced knee recurvatum and increased ankle dorsiflexion over three months.
- The findings suggest a potential connection between the noxious stimulus from the bladder stone and increased spasticity, indicating that spinal reflexes can influence muscle tone and movement in individuals with spinal cord injuries.
The Relationship Between Neighborhood Disadvantage and Markers of Chronic Pain Risk: Findings From the Oklahoma Study of Native American Pain Risk (OK-SNAP).
J Pain
September 2024
Department of Psychology, The University of Tulsa, Tulsa, Oklahoma; Department of Health Promotions Sciences, University of Oklahoma Health Sciences Center, Tulsa, Oklahoma. Electronic address:
Socioeconomic disadvantage contributes to health inequities, including chronic pain. Yet, research examining socioeconomic disadvantage and pain risk in Native Americans (NAs) is scant. This exploratory analysis assessed relationships between socioeconomic position (SEP), ethnicity, and neighborhood disadvantage on pronociceptive processes in 272 healthy, chronic pain-free NAs (n = 139) and non-Hispanic Whites (NHWs, n = 133) from the Oklahoma Study of Native American Pain Risk (OK-SNAP).
View Article and Find Full Text PDFThe Effect of Experimentally Induced Pain in the Cervical, Shoulder, or Orofacial Regions on Cervical Neuromuscular and Kinematic Features: A Systematic Review and Meta-analysis.
J Pain
December 2024
School of Sport, Exercise and Rehabilitation Sciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, UK; Centre of Precision Rehabilitation for Spinal Pain (CPR Spine), School of Sport, Exercise and Rehabilitation Sciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, UK. Electronic address:
In this systematic review, we synthesize the literature investigating the effect of experimentally induced pain in the cervical, shoulder, or orofacial regions on cervical neuromuscular and kinematic features. Databases were searched up to November 1, 2023. A total of 29 studies using hypertonic saline injection (n = 27) or glutamate injection (n = 2) as experimental pain models were included.
View Article and Find Full Text PDFA randomized double-blind active-controlled clinical trial on the efficacy of topical basil () oil in knee osteoarthritis.
Front Pharmacol
May 2024
Research Center for Traditional Medicine and History of Medicine, Department of Persian Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Background: Basil is a widely used herb in Persian medicine and is gaining recognition as a functional food worldwide.
Aim Of The Study: This trial aimed to assess the effectiveness of a traditional formulation of basil oil in comparison with diclofenac gel in treating knee osteoarthritis, considering its established anti-inflammatory, anti-nociceptive, and anti-oxidative properties.
Materials And Methods: One hundred eligible patients were equally randomized to the traditional basil oil (containing sesame oil) and diclofenac gel groups.
Pain reflects the informational value of nociceptive inputs.
Pain
October 2024
Department of Psychology, McGill University, 2001 McGill College, Montréal, QC, Canada.
Pain perception and its modulation are fundamental to human learning and adaptive behavior. This study investigated the hypothesis that pain perception is tied to pain's learning function. Thirty-one participants performed a threat conditioning task where certain cues were associated with a possibility of receiving a painful electric shock.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!