Purpose: To compare the heparin-surface-modified and the regular polymethylmethacrylate posterior chamber intraocular lenses regarding cellular reactions one year after extracapsular cataract extraction.
Material And Methods: 62 patients of either sex, with senile cataract, without diabetes and any preoperative pathology of the eye, were included in the study. 30 patients received HSM PMMA PC IOL and 32 patients received unmodified PMMA PC IOL. All patients had a standard extracapsular cataract extraction. At the examination after one year the best corrected visual acuity was defined, anterior segment of the eye was evaluated biomicroscopically, cell deposits were assessed and the state of posterior capsule was noticed.
Results: One year postoperatively all patients in both groups had the best corrected visual acuity better than 0.5. Significantly fewer eyes with the HSM PMMA PC IOLs had cell deposits on the anterior surface of the lens (20% vs. 37.5%). The amount of cell deposits per patients was small. Irregularity of the pupil with presence of posterior synechias did not differ significantly between the groups. The percentage of patients with clear posterior capsule was greater in the group with implanted heparin-modified artificial lenses.
Conclusion: The study suggests that heparin-surface-modified posterior intraocular lenses result in less postoperative cellular response observed one year after extracapsular cataract extraction.
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J Perioper Pract
January 2025
University of Derby, Derby, UK.
This historical research article offers a comprehensive examination of the evolution of cataract surgery from ancient practices to modern innovations. The historical trajectory of cataract treatment will be explored, beginning with ancient techniques such as couching in ancient civilisations and progressing through critical milestones in surgical advancement. The research delves into the challenges faced by early practitioners, the emergence of novel techniques and the pivotal contributions of pioneering surgeons throughout history.
View Article and Find Full Text PDFIntroduction Cataracts are the leading cause of blindness worldwide, with a notably high incidence rate. Endophthalmitis is the most severe complication following cataract surgery , often resulting in profound vision loss. This study evaluates the impact of risk factors such as age, sex, diabetes mellitus (DM), hypertension, posterior capsule rupture (PCR), type of surgery, and use of intraocular lens (IOL) material on the risk of endophthalmitis after cataract surgery.
View Article and Find Full Text PDFArch Soc Esp Oftalmol (Engl Ed)
December 2024
Fundación Elena Barraquer, Barcelona, Spain; Qvision, VITHAS Hospital, Almería, Spain.
The aim of this article has been, on the one hand, to describe the use of MSICS (manual small incision cataract surgery) for the management of cataracts, especially mature ones, in relation to its particular utility in the field of humanitarian campaigns, for which a description of the MSICS technique has been made, subsequently a review of the available scientific literature has been carried out to verify the results of this technique in comparison with phacoemulsification and extracapsular surgery and to describe the importance of teaching this technique to all cataract surgeons, especially the ones participating in humanitarian campaigns. According to what has been found, MSICS is an excellent surgical technique and according to current evidence it seems to be the choice over phacoemulsification and/or the classic extracapsular technique in hyper mature cataracts, especially in the field of humanitarian campaigns, due to its lower rate of complications and the improvement in visual acuity obtained. According to the studies found, it would be possible for the experienced ophthalmologic surgeon to implement this technique since the learning curve is short.
View Article and Find Full Text PDFCureus
November 2024
Department of Obstetrics and Gynecology and Urology, New York Medical College, Valhalla, USA.
Background The United States continues to rank as one of the most expensive healthcare systems in the world, and cataract surgery, the most commonly performed surgery, is one of the primary drivers of healthcare expenditure. Increasing efforts have been made to try to minimize U.S.
View Article and Find Full Text PDFInvest Ophthalmol Vis Sci
December 2024
Eye Center of Xiangya Hospital, Central South University, Changsha, China.
Purpose: Inflammation, oxidative stress, and epithelial-mesenchymal transition (EMT) play crucial roles in forming posterior capsular opacification (PCO), particularly in fibrotic PCO. Here we investigated the protective effects of mefunidone (MFD), a novel compound with potent antifibrotic properties, which could be useful in preventing PCO.
Methods: We utilized an extracapsular lens extraction (ECLE) surgery in mice to simulate the development of PCO in vivo.
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