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Dual Hepatic Injury from Refeeding Syndrome and Starvation in a Malnourished Woman After Bariatric Surgery: A Case Report.

Am J Case Rep

October 2024

Department of Endocrinology and Metabolism, Shanghai Jiao Tong University School of Medicine Affiliated Sixth People's Hospital, Shanghai Clinical Center for Diabetes, Shanghai Key Clinical Center for Metabolic Disease, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai, China.

BACKGROUND Refeeding syndrome (RFS) and starvation-associated injuries are significant complications in malnourished patients. Severe weight loss after obesity surgery is frequently associated with malnutrition, consequently increasing the likelihood of RFS and starvation-related injuries as postoperative complications. RFS and starvation-induced injury in a single patient has rarely been reported.

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Article Synopsis
  • - Refeeding syndrome is a serious complication that can occur in children suffering from severe acute malnutrition (SAM) when high-caloric feeding is resumed, particularly affecting electrolyte levels like phosphorus, potassium, and magnesium, with hypophosphatemia being a key indicator.
  • - The study aimed to investigate how often refeeding syndrome occurs and what factors contribute to it during the transition phase of treatment for SAM in children aged 6 to 59 months at a hospital in Uganda.
  • - Out of 150 children studied, 115 were analyzed, and 34.8% developed refeeding syndrome, highlighting that close monitoring of electrolyte levels is crucial during treatment of SAM to prevent this condition.
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The Incidence and Risk Factors of Refeeding Syndrome-like Hypophosphatemia in Inflammatory Bowel Disease: A Preliminary Study.

J Gastrointestin Liver Dis

September 2024

Department of Clinical Nutrition, Erciyes University Health Science Institute, Kayseri; Division of Medical Intensive Care, Department of Internal Medicine, Erciyes University School of Medicine, Kayseri, Turkey.

Article Synopsis
  • Refeeding syndrome (RFS) is linked to serious electrolyte imbalances like hypophosphatemia, especially in hospitalized patients with inflammatory bowel disease (IBD), which can be worsened by malnutrition and severity of the disease.
  • In a study of 50 IBD patients, 46% experienced hypophosphatemia during the first week of hospitalization, with significant correlations found between low phosphate levels and both potassium concentrations and disease severity.
  • Factors such as malnutrition, the use of parenteral nutrition, and severe IBD were identified as significant predictors for developing hypophosphatemia in these patients, highlighting the need for careful monitoring and management.
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Phosphate level changes in oral cancer patients - recognizing the risk for refeeding syndrome.

Eur Arch Otorhinolaryngol

September 2024

Department of Oral and Maxillofacial Diseases, Clinicum, Faculty of Medicine, University of Helsinki, Helsinki University Hospital, Helsinki, Finland.

Purpose: Patients with oral squamous cell carcinoma (OSCC) often have difficulties in obtaining sufficient nutrition and may develop refeeding syndrome (RFS) during hospitalization. RFS may be fatal if not treated properly. This study clarified changes in perioperative phosphate levels and occurrence of RFS symptoms in OSCC patients to identify clinically notable predisposing factors for RFS in this specific patient population.

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High-calorie refeeding in adolescents with anorexia nervosa: a narrative review.

Acta Gastroenterol Belg

August 2024

Hôpital Erasme, Hôpital Universitaire de Bruxelles (HUB), Université Libre de Bruxelles (ULB), Brussels, Belgium.

Article Synopsis
  • Recent studies suggest that starting with a high-calorie diet for refeeding in anorexia nervosa (AN) may be beneficial, particularly for hospitalized children and adolescents.* -
  • A review of 15 studies, mostly observational, indicated that initial energy intake during refeeding can vary widely but generally starts higher than current recommendations, showing better weight restoration outcomes with high-calorie refeeding (HCR).* -
  • The findings highlight the potential for safe high-calorie refeeding in low-risk adolescents with AN, but call for more comprehensive research to establish a standardized protocol and ensure safety, particularly for severely malnourished patients.*
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