Nine patients with moderate to severe chronic obstructive lung disease were grouped according to results of pulmonary function testing. After a short period of 100 percent oxygen breathing, it took on the average 20 minutes (range--18 to 24 minutes) for their partial pressure of arterial oxygen to return to baseline levels. These data suggest that, after discontinuing supplemental oxygen in patients with chronic airways obstruction, more than 25 minutes should elapse if a blood gas measurement is to reflect with certainty conditions during room air breathing.
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