Objective: To investigate the presence or absence of procalcitonin in the seminal plasma of both normal and subfertile men.
Design: Controlled clinical study.
Setting: Academic research environment.
Patient(s): Healthy male volunteers and subfertile men with varicocele or infection of the male accessory glands.
Intervention(s): None.
Main Outcome Measure(s): Seminal plasma procalcitonin determinations.
Result(s): Seminal plasma procalcitonin levels from subfertile men were not significantly different from those found in healthy volunteers.
Conclusion(s): Although procalcitonin can be detected in the seminal plasma, these preliminary results indicate that it cannot be used as a diagnostic marker.
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http://dx.doi.org/10.1016/s0015-0282(00)01588-0 | DOI Listing |
BMC Vet Res
January 2025
Technology Center, Hohhot Customs District, Hohhot, 010020, Inner Mongolia, China.
Background: Bovine viral diarrhoea virus genotype 1 (BVDV-1) and bluetongue virus (BTV) are potent viral pathogens that may be transmitted through semen, resulting in the spread of diseases via artificial insemination. Thus, establishing an early detection method for BVDV-1 and BTV infection is important for the trading of semen. In this study, we developed two RT‒ddPCR methods to detect BVDV-1 and BTV, and each method was evaluated for repeatability, limit of detection and specificity.
View Article and Find Full Text PDFReprod Sci
January 2025
Department of Embryology, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran.
The metabolomic approach has recently been used in the assessment of semen quality and male fertility. Additionally, the crucial roles of branched-chain amino acids (BCAAs) and aromatic amino acids (AAAs) in metabolic syndrome (MetS) were reported. However, little information exists about the association between BCAAs and AAAs with semen parameters, particularly in men with and without MetS.
View Article and Find Full Text PDFPhytomedicine
January 2025
Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou 221004, PR China. Electronic address:
Background: Renal tubular injury was a significant pathological change of diabetic kidney disease (DKD), and the amelioration of renal tubular injury through mitochondrial function was an important treatment strategy of DKD. Our previous study had revealed that Jujuboside A (Ju A), the main active substance isolated from Semen Ziziphi Spinosae (SZS), could restore renal function of diabetic mice. However, its protective mechanism against DKD remains unclear.
View Article and Find Full Text PDFJ Hazard Mater
January 2025
Chongqing Key Laboratory of Forage & Herbivore, College of Veterinary Medicine, Southwest University, Beibei, Chongqing 400715, PR China. Electronic address:
Heat stress negatively affects pig production by disrupting the immune homeostasis of Sertoli cells (SCs), which compromises sperm quality, culminating in male infertility. Herein, we aimed to study the mechanism by which the NLRP3 inflammasome is activated by heat stress through N6-methyladenosine (mA) modification regulation in SCs. Initially, it was found that heat stress (44°C, 30 min) markedly activated ERK1/2 signaling, which subsequently promoted NLRP3 inflammasome activation and inflammatory cytokine release from SCs.
View Article and Find Full Text PDFAnim Reprod Sci
January 2025
Department of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, Italy.
This work aimed to evaluate whether supplementing the freezing extender with olive fruit extract (OFE) would improve the antioxidant defense of buffalo sperm, resulting in improved post-thaw semen quality. Ejaculates (two per 16 Murrah buffalo bulls) were split into four aliquots that were diluted in an extender supplemented with different doses of OFE (0, D50, D100, and D150, based on µM concentrations of hydroxytyrosol, the most represented polyphenol) and frozen according to standard procedures. At thawing, sperm motility, kinetics, viability, acrosome integrity, and membrane functionality were evaluated.
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