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Pierre Fauchard's Contribution to Oral Medicine and Oral and Maxillofacial Pathology: An historical essay.
J Hist Dent
August 2024
Department of Molecular Pathobiology, New York University College of Dentistry, New York, NY, USA.
Article Synopsis
- Pierre Fauchard, known as the father of dentistry, made significant contributions to various dental fields, although his impact on oral medicine and maxillofacial pathology was previously overlooked.
- This study aimed to uncover Fauchard’s work on oral diseases by analyzing both French and English sources, gathering information on diagnosed and treated conditions.
- The research identified his contributions to diseases like scurvy, abscesses, and oral ulcers, highlighting his importance in diagnosing and treating various oral health issues relevant to modern dentistry.
Scurvy. A forgotten pseudovasculitis.
Reumatol Clin (Engl Ed)
May 2024
Servicio de Reumatología, Complexo Hospitalario Universitario de Pontevedra, Pontevedra, Spain.
Scurvy is a nutritional disease caused by ascorbic acid (vitamin C) deficiency. Althought currently it is a rare disease, we should considerer it in the differential diagnosis of purpura and arthritis in patients with restrictive diets. We present the case of a 49-year-old man with a history of a nutritional disorder presented to our hospital with generalized purpura and hemarthros.
View Article and Find Full Text PDFA case report of a childhood scurvy musculoskeletal manifestation: Radiologic findings and diagnostic implications.
Radiol Case Rep
August 2024
Department of Radiology, Doctor Soedarso General Hospital, Pontianak, Indonesia.
Scurvy is an infrequent pathological condition resulting from a sustained dietary vitamin C deficiency. Radiology becomes pivotal because the diagnostic process for scurvy can be intricate, given its resemblance to bone neoplasms. A 6-year-old boy, reported persistent pain and swelling in the right thigh for 2 months prior to hospitalization.
View Article and Find Full Text PDFVitamin C deficiency alters the transcriptome of the rat brain in a glucocorticoid-dependent manner, leading to microglial activation and reduced neurogenesis.
J Nutr Biochem
June 2024
Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, Japan; Graduate School of Agriculture, Tokyo University of Agriculture and Technology, Fuchu, Tokyo, Japan. Electronic address:
Article Synopsis
- Vitamin C (VitC) is crucial for brain function, and its deficiency leads to neuropsychiatric issues like depression and cognitive decline, but the exact molecular mechanisms are unclear.
- RNA sequencing in ODS rats revealed that short-term VitC deficiency alters gene expression related to glucocorticoid receptors, with increased glucocorticoid secretion from the adrenal gland.
- VitC deficiency also triggers microglial activation and inflammation in the brain, reduces the generation of new neurons, and suggests the necessity of VitC for adult neurogenesis critical for learning and memory.
Scurvy in a young man: a rare case report.
Front Nutr
October 2023
Department of Rheumatology and Immunology, Shenzhen People's Hospital, Shenzhen, China.
Article Synopsis
- Scurvy is caused by a deficiency of vitamin C, leading to general symptoms like weakness, malaise, and fatigue, which can make it easy to misdiagnose.
- Recent cases of scurvy in children are rare, and it’s even less common in young adults.
- A 25-year-old male, with no prior health issues, experienced severe pain and bruising in his legs due to a lack of outdoor activity and poor diet, ultimately being diagnosed with scurvy.
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