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http://dx.doi.org/10.1099/00221287-146-12-3285DOI Listing

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Article Synopsis
  • Paratuberculosis, or Johne's disease, is a contagious bacterial infection affecting ruminants, including certain wild and domestic animals, and is recognized under the new EU Animal Health Law requiring surveillance.
  • A study conducted in Stelvio National Park, Italy, from 2018 to 2022 analyzed 390 red deer for Mycobacterium avium subspecies paratuberculosis (MAP), finding a 5.9% prevalence overall, which declined over the years.
  • The research indicated that older deer and those with lower body mass were more likely to test positive for MAP, suggesting early stages of the infection with minimal signs of disease in the population.
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Background: A 26-year-old male had a history of frequent bowel movements, mushy stool with mucus and loss of 25 kg body weight in 6 months was diagnosed as a case of inflammatory bowel disease (IBD). The patient did not respond to routine and standard treatment for IBD. His condition was steadily deteriorating, and he was in a very precarious state when he reported to us.

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subsp. () is the etiological agent of Johne's disease in ruminants. The IS insertion sequence (IS) has been used widely as an epidemiological marker and target for PCR diagnosis.

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Background: Mycobacterium avium subsp. paratuberculosis (Map) causes Johne's disease (JD), a chronic enteritis widespread in ruminants, resulting in substantial economic losses, especially to the dairy industry. Understanding the genetic diversity of Map in Australia will assist epidemiological studies for tracking disease transmission and identify subtype characteristics for use in development of improved diagnostic typing methods.

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The objectives of the present study were to characterize subsp. (MAP) infection using serological and molecular tools and investigate the distribution and molecular characterization of MAP strains (cattle (C) and sheep (S) types) in sheep, goat, cattle, and camel herds in Eastern Province, Saudi Arabia. Serum and fecal samples were collected from all animals aged >2 years old in 31 herds (sheep = 8, goats = 6, cattle = 8 and camels = 9) from January to December 2019.

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