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Effect of implementing training programme for nurses about care bundle on prevention of ventilator-associated pneumonia among newborns.
Nurs Crit Care
March 2025
Pediatric Nursing Department, Faculty of Nursing, Damanhur University, Damanhur City, Egypt.
Background: Ventilator-associated pneumonia (VAP) is a frequent and severe complication among newborns in neonatal intensive care units (NICUs). It is associated with elevated morbidity and mortality rates, more extended hospital stays and increased health care costs. Implementing preventive care bundles and structured sets of evidence-based practices reduces VAP incidence.
View Article and Find Full Text PDFEvaluation of the Patient-Specific Functional Scale for monitoring paediatric injury patients at a zonal referral hospital in Northern Tanzania.
BMJ Paediatr Open
March 2025
Kilimanjaro Christian Medical University College, Moshi, Tanzania, United Republic of.
Background: Injuries are a major cause of morbidity and mortality among paediatric populations in low- and middle-income countries (LMICs). The Patient-Specific Functional Scale (PSFS) is a commonly used tool to assess functional recovery. This study aims to evaluate the psychometric properties of the PSFS for monitoring paediatric injury patients at a zonal referral hospital in Northern Tanzania.
View Article and Find Full Text PDFIdentification of distinct clinical profiles of sepsis risk in paediatric emergency department patients using Bayesian profile regression.
BMJ Paediatr Open
March 2025
Children's Intensive Care Research Program, Child Health Research Centre, The University of Queensland, South Brisbane, Queensland, Australia.
Background: Sepsis affects 25 million children and neonates annually, causing significant mortality and morbidity. Early identification and treatment are crucial for improving outcomes. Identifying children at risk is challenging due to clinical heterogeneity and overlap with other conditions.
View Article and Find Full Text PDF[Is previable rupture of membranes an independent neonatal prognostic factor from the gestational age at birth?].
Gynecol Obstet Fertil Senol
March 2025
Département mère-enfant, Institut mutualiste Montsouris, Paris, France.
Objective: Compare, at the same gestational age at birth, survival without severe neonatal morbidity among live-born infants after previable premature rupture of membranes (PROM) occurring before 22 weeks of gestation (WG) versus at or after 22 weeks.
Methods: Retrospective study conducted in a tertiary care referral center between 2016 and 2021, including live births between 23 and 36 weeks + 6 days after PROM. Only live-born infants with neonatal resuscitation care were included.
Unlocking the Potential of MicroRNA Expression: Biomarkers for Platelet Reactivity and Coronary Artery Disease.
Semin Thromb Hemost
March 2025
Department of Cardiology, Aalborg University Hospital, Aalborg, Denmark.
Coronary artery disease (CAD) is a leading cause of morbidity and mortality worldwide, with platelet reactivity playing a central role in its pathogenesis. Recent research has identified microRNAs (miRNAs; miRs) as potential biomarkers for CAD, due to their ability to regulate platelet function and reactivity. This review focuses on four key miRNAs-miR-223, miR-126, miR-21, and miR-150-known to influence platelet reactivity and their implications in CAD.
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