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An easy-to-use three-dimensional protein-structure-prediction online platform "DPL3D" based on deep learning algorithms.
Curr Res Struct Biol
June 2025
The College of Health Humanities, Jinzhou Medical University, Jinzhou, 121001, China.
The change in the three-dimensional (3D) structure of a protein can affect its own function or interaction with other protein(s), which may lead to disease(s). Gene mutations, especially missense mutations, are the main cause of changes in protein structure. Due to the lack of protein crystal structure data, about three-quarters of human mutant proteins cannot be predicted or accurately predicted, and the pathogenicity of missense mutations can only be indirectly evaluated by evolutionary conservation.
View Article and Find Full Text PDFSexual and reproductive health content in Australian pre-registration nursing and midwifery programs: A review of curricula.
Nurse Educ Pract
January 2025
Monash University, SPHERE, NHMRC Centre of Research Excellence, School of Public Health and Preventive Medicine, 553 St Kilda Road, VIC 3004, Australia; Monash University, Department of General Practice, School of Public Health and Preventive Medicine, 553 St Kilda Road, VIC 3004, Australia. Electronic address:
Aim: To identify and examine sexual and reproductive health (SRH) content in Australia's pre-registration undergraduate and postgraduate Nursing and Midwifery program curricula.
Background: Sexual and reproductive healthcare, integral to women's well-being, relies on Nursing and Midwifery workforce. However, it is unknown how pre-registration curricula prepares nurses and midwives to provide this care, despite international imperatives to enhance access.
People with aphasia show stable Cumulative Semantic Interference (CSI) when tested repeatedly in a web-based paradigm: A perspective for longitudinal assessment.
Cortex
December 2024
Humboldt-Universität zu Berlin, Berlin School of Mind and Brain, Berlin, Germany; Max Planck Institute for Human Cognitive and Brain Sciences, Department of Neurology, Leipzig, Germany; University Hospital and Faculty of Medicine Leipzig, Clinic for Cognitive Neurology, Leipzig, Germany.
Retrieving words quickly and correctly is an important language competence. Semantic contexts, such as prior naming of categorically related objects, can induce conceptual priming but also lexical-semantic interference, the latter likely due to enhanced competition during lexical selection. In the continuous naming (CN) paradigm, such semantic interference is evident in a linear increase in naming latency with each additional member of a category out of a seemingly random sequence of pictures being named (cumulative semantic interference/CSI effect).
View Article and Find Full Text PDFAnatomic Variations Important for Dental Implantation in the Mandible-A Systematic Review.
Diagnostics (Basel)
January 2025
Department of Anatomy, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia.
: This is a systematic review on the subject of anatomic landmarks and variations in the mandible that influence implantation placement. With this systematic review, we would like to summarize the results from different studies that are relevant to this subject and that are up to date, presenting their main findings, the measurements of mentioned landmarks, and giving clinical implications that will be helpful to practitioners in their better understanding of this topic. : This study followed all of the elements of PRISMA.
View Article and Find Full Text PDFSmokeless tobacco: knowledge, attitudes and usage in Pakistan.
J Health Popul Nutr
January 2025
Section of Pulmonology and Critical Care, Department of Medicine, Aga Khan University Hospital, Karachi, 74800, Pakistan.
Background: Smokeless tobacco (SLT) encompasses products that are not burnt but instead consumed orally or nasally. One-third of tobacco is consumed in the smokeless form in South Asia. Despite its widespread usage, there has been limited empirical research on the prevalence and factors influencing SLT consumption in Pakistan.
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