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De novo transcriptome assembly and analysis during agarwood induction in Gyrinops versteegii Gilg. seedling.
Sci Rep
January 2025
Plant Science and Biotechnology Research Group, School of Life Sciences and Technology, Institut Teknologi Bandung, West Java, 40132, Indonesia.
Agarwood is a highly prized resinous wood produced by select members of the Thymelaeaceae plant family. Its formation in Aquilaria species has been expedited using various induction techniques, revealing insights into factors affecting the chemical constituents of artificially induced agarwood. Building on this, our research delved into the potential of another Thymelaeaceae member, Gyrinops versteegii, as an alternate agarwood source.
View Article and Find Full Text PDFClinical and immunological outcomes after randomized trial of baked milk oral immunotherapy for milk allergy.
JCI Insight
January 2025
Division of Pediatric Allergy, Immunology, and Rheumatology, Department of Pediatrics, John Hopkins University School of Medicine, Baltimore, Maryland, USA.
BACKGROUNDCow's milk (CM) allergy is the most common food allergy in young children. Treatment with oral immunotherapy (OIT) has shown efficacy, but high rates of adverse reactions. The aim of this study was to determine whether baked milk OIT (BMOIT) could reduce adverse reactions while still inducing desensitization, and to identify immunological correlates of successful BMOIT.
View Article and Find Full Text PDFA 30-Min Exposure on Permethrin and Deltamethrin Modifies Ion Transport Pathways in the Skin.
Biomolecules
November 2024
Laboratory of Electrophysiology of Epithelial Tissue and Skin, Department of Pathobiochemistry and Clinical Chemistry, Faculty of Pharmacy, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, M. Skłodowskiej-Curie 9, 85-094 Bydgoszcz, Poland.
Pyrethroids are pesticides used in agriculture, the textile industry, wood processing, and human and animal medicine. Pyrethroids inhibit voltage-sensitive sodium channels (VSSCs) in insects and mammals. It results in the premature opening and/or delayed closing of the channels, causing a prolonged influx of Na ions into the cell.
View Article and Find Full Text PDFRole of Inflammation and Cytokine Dysregulation in Depression in Patients with Inflammatory Skin Conditions.
Am J Clin Dermatol
January 2025
Psychiatry, College of Medicine/CMU Medical Education Partners Saginaw, Central Michigan University, Saginaw, MI, USA.
Article Synopsis
- Psychodermatology examines how skin and mental health issues relate, especially in patients with inflammatory skin conditions and depression.
- The review identifies a strong connection between proinflammatory cytokines involved in skin diseases and depressive symptoms, suggesting shared biological pathways.
- Co-managing skin and psychiatric disorders through interdisciplinary approaches can improve patient outcomes and necessitates further research into these links for potential new treatments.
Minimizing Indoor Allergen Exposure: What Works?
Curr Allergy Asthma Rep
November 2024
Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States.
Purpose Of Review: Allergic rhinitis and asthma morbidity has been linked to indoor allergen exposure. Common indoor allergens include dust mites, cats, dogs, rodents, and cockroaches. These allergens are ubiquitous and often difficult to remove from the home, making long-lasting reduction strategies difficult to achieve.
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