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Availability, pricing, and affordability of antithrombotic medicines in Addis Ababa, Ethiopia: implications for health policy.
J Pharm Health Care Sci
January 2025
Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Science, Addis Ababa University, Addis Ababa, Ethiopia.
Background: Antithrombotic medications are essential for the management of abnormal clot formation. However, their availability, pricing, and affordability in Ethiopia, particularly in Addis Ababa, have not been comprehensively studied.
Methods: A cross-sectional study was conducted in Addis Ababa, Ethiopia to assess the availability, pricing, and affordability of essential antithrombotic medicines.
A trial of radiolabeled antibody yttrium-90-FF-21101 for the treatment of advanced ovarian and other cancers.
Cancer
January 2025
Stephenson Cancer Center, University of Oklahoma Health Sciences Center/Sarah Cannon Research Institute, Oklahoma City, Oklahoma, USA.
Background: Yttrium-90 FF-21101 (Y-FF-21101) is a radiopharmaceutical that targets P-cadherin as a therapy against solid tumors. A previously reported, first-in-human study determined that a dose of 25 mCi/m was safe, and a patient with clear cell carcinoma of the ovary achieved a complete response. In this article, the authors report the results of Y-FF-21101 treatment in an ovarian carcinoma expansion cohort and in patients with selected solid tumors who had known high P-cadherin expression.
View Article and Find Full Text PDFPrices, availability, and affordability of adult medicines in 54 low-income and middle-income countries: evidence based on a secondary analysis.
Lancet Glob Health
January 2025
School of Pharmacy, Faculty of Medicine and Health, University of Sydney, Sydney, NSW, Australia.
Background: Medication shortages are a pressing concern throughout the world. To gain insight into this issue, WHO and Health Action International (HAI) have constructed a validated method to survey medicine prices, availability, and affordability in low-income and middle-income countries. This paper aims to present an updated analysis of medicine affordability, availability, and pricing across 54 countries using the WHO-HAI method, highlighting disparities between public and private sectors.
View Article and Find Full Text PDFCharacteristics of Children, Youth, and Young Adults With Diabetes: A Cross-Sectional Study in New Zealand Aotearoa.
J Diabetes Res
December 2024
Medical Research Centre, Te Huataki Waiora School of Health, University of Waikato, Hamilton, New Zealand.
The prevalence of diabetes mellitus among children, youth, and young adults is increasing, yet limited information is known about the characteristics and management of these groups with Type 1 (T1D) and Type 2 (T2D) diabetes in primary care. The aim of the study is to explore the characteristics of people with T1D and T2D aged < 25 years across the Auckland and Waikato regions of New Zealand. : Sociodemographic and clinical data were collected from electronic primary care records (February 2021-July 2022) of four primary healthcare organisations, with medication data sourced from the National Pharmaceutical dataset.
View Article and Find Full Text PDFNanotechnology in Pain Management.
Pharmaceutics
November 2024
Department of Anesthesiology, Stony Brook University Hospital, Stony Brook, NY 11794, USA.
Article Synopsis
- Chronic pain affects millions globally, leading to significant loss in wages and increasing healthcare costs due to dependency on traditional pain medications with serious side effects.
- Common medications like opioids and NSAIDs can result in harmful complications and serious risks such as addiction and overdose, prompting a critical need for alternative treatments.
- Nanotechnology offers promising solutions for chronic pain relief by creating advanced drug delivery systems that enhance efficacy while minimizing side effects, with innovative methods including nanocapacitor patches and gene therapy being explored.
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