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Lack of fibro-inflammatory response in human mammary adipose tissue in obesity.
Int J Obes (Lond)
December 2024
Institut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, Université Toulouse III-Paul Sabatier (UT3), Toulouse, France.
Background: Understanding how obesity impacts human mammary adipose tissue (MAT) biology is crucial for deciphering its role in mammary epithelium during both physiological and pathophysiological processes, including breast cancer. Hypertrophic mammary adipocytes and Crown-Like Structures are present in MAT of patients with obesity but whether these changes initiate a fibro-inflammatory response at the tissue level remains insufficiently explored.
Objective: We investigated the markers of adipose tissue dysfunction (immune cell infiltration, secretion pattern and fibrosis) in tumor-free MAT of patients with obesity versus patients who are lean.
Effect of Moderate Red Meat Intake Compared With Plant-Based Meat Alternative on Psychological Well-Being: A 10-Wk Cluster Randomized Intervention in Healthy Young Adults.
Curr Dev Nutr
January 2025
Discipline of Nutrition, School of Medical Sciences, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand.
Background: A healthy diet has been proposed to support good mental health, but the addition of either red meat or meat alternatives is nuanced.
Objectives: We aimed to determine if psychological and physiological well-being is differentially affected by consuming recommended weekly amounts of either lean red meat or plant-based meat alternatives (PBMAs) supplemented with a plant-rich diet.
Methods: The trial was a parallel 2-arm randomized intervention of 10 wk duration.
Beyond knowledge: Unveiling the hidden link between body image and dietary intake in elite race walkers at risk of relative energy deficiency in sport.
Nutr Health
December 2024
Population Health and Exercise Science, New Jersey City University, Jersey City, NJ, USA.
Nutritional knowledge and body image concerns are key factors influencing dietary intake and health among athletes, particularly in lean-type sports. This study investigates these variables among elite race walkers from the United Kingdom and Ireland, a cohort selected for the prominence of race walking in their national sports programmes and unique cultural contexts. The study aims to assess the relationship between nutritional knowledge, body image, and dietary intake in elite race walkers, and explore the potential risk of relative energy deficiency in sport (RED-S).
View Article and Find Full Text PDFDynamic Alignment Changes of the Spine, Pelvis, and Lower Limbs during Gait Analyzed Using Inertial Motion Capture in Patients with Adult Spinal Deformity.
Spine Surg Relat Res
November 2024
Department of Orthopaedic Surgery, Dokkyo Medical University, Mibu, Japan.
Introduction: Patients with adult spinal deformity (ASD) lean forward with their trunks when walking, even if they can remain upright during static standing. However, it remains unclear which part of the spinal column is involved in forward trunk tilt and the details of the relationships between sagittal alignment during static standing and changes in dynamic parameters during walking. Therefore, this study aimed to clarify the above by analyzing the walking motion of ASD patients using inertial measurement units (IMUs).
View Article and Find Full Text PDFTibetan red deer () diet composition patterns and associations during lean seasons in Tibet, China.
PeerJ
December 2024
College of Wildlife and Protected Area, Northeast Forestry University, Harbin, Heilongjiang Province, China.
Tibetan red deer () in the high-altitude environment of the Qinghai-Tibet Plateau could face seasonal challenges from food shortages and nutritional deficiencies but the nutritional requirements are complex. Analyzing diet composition pattern(s) is the first step to disentangle this complexity. From a systematic perspective, we hypothesize that: (A) diet composition pattern or patterns exist within the population and (B) a portion of the diet beyond characterized diet combinations will consist of random combinations.
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