Thoracic paragangliomas are a rare cause of hypertension. We report the occurrence of a sporadic benign norepinephrine-producing branchiomeric paraganglioma in a 32-year-old man with paroxysms of hypertension. After localization by iodine 123-metaiodobenzyl-guanidine scintigraphy and magnetic resonance imaging, the paraganglioma was resected successfully below the right pulmonary artery through a right-sided posterolateral thoracotomy. The particular location was consistent with a branchiomeric paraganglioma in an extremely rare extrapulmonary location.
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http://dx.doi.org/10.1016/s0003-4975(00)01901-9 | DOI Listing |
Malays J Pathol
June 2009
Department of Pathology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Extra-adrenal paragangliomata are uncommon entities. They can be classified into four basic groups according to their anatomical sites, i.e.
View Article and Find Full Text PDFActa Otorrinolaringol Esp
February 2009
Departamento de Anatomía Humana, Facultad de Medicina, Universidad de Salamanca, Salamanca, Spain.
Paragangliomas are tumors that arise in the extraadrenal paraganglia and result from migration of neural crest cells during embryonic development. Based on their anatomical distribution, innervation and microscopic structure, these tumors can be classified into interrelated families: branchiomeric paraganglia (related to the branchial clefts and arches), intravagal, aortic-sympathetic and visceral-autonomic. Head and neck paragangliomas belong mainly to the first two of these families.
View Article and Find Full Text PDFAJR Am J Roentgenol
April 2007
Department of Radiology, University of Pennsylvania School of Medicine, Hospital of the University of Pennsylvania, 3400 Spruce St., Philadelphia, PA 19104, USA.
Objective: Our purpose was to show the CT and MRI findings of paragangliomas of the aortic body and the great vessels of the mediastinum.
Conclusion: Paragangliomas of the aortic body and the great vessels have a characteristic imaging appearance. They originate from known sites of the branchiomeric paraganglia such as the aortic body.
Am J Pathol
June 2001
Josephine Nefkens Institute, Erasmus University Medical Center, Rotterdam, the Netherlands.
Parasympathetic paragangliomas (PGLs) represent neuroendocrine tumors arising from chief cells in branchiomeric and intravagal paraganglia, which share several histological features with their sympathetic counterpart sympathoadrenal paragangliomas. In recent years, genetic analyses of the familial form of PGL have attracted considerable interest. However, the majority of paragangliomas occurs sporadically and it remains to be determined whether the pathogenesis of sporadic paraganglioma resembles that of the familial form.
View Article and Find Full Text PDFAnn Thorac Surg
November 2000
Department of Medicine II, Klinikum Grosshadern, Ludwig-Maximilians-University, Munich, Germany.
Thoracic paragangliomas are a rare cause of hypertension. We report the occurrence of a sporadic benign norepinephrine-producing branchiomeric paraganglioma in a 32-year-old man with paroxysms of hypertension. After localization by iodine 123-metaiodobenzyl-guanidine scintigraphy and magnetic resonance imaging, the paraganglioma was resected successfully below the right pulmonary artery through a right-sided posterolateral thoracotomy.
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