Solid-phase synthesis of di- and tripeptidic hydroxamic acids as inhibitors of procollagen C-proteinase.

Bioorg Med Chem Lett

Roche Bioscience, Inflammatory Diseases Unit, Palo Alto, CA 94304, USA.

Published: November 2000

A solid-phase approach to the rapid synthesis of di- and tripeptide-like hydroxamic acids is presented. These compounds are shown to be potent inhibitors of procollagen C-proteinase (PCP).

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Source
http://dx.doi.org/10.1016/s0960-894x(00)00525-4DOI Listing

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