The tissue reaction in rabbit iris and cornea to prolene suture is equivalent to the tissue reaction to nylon suture. The prolene suture retains its tensile strength indefinitely and this may make it particularly useful in situations where a permanent suture is desired, such as in refractive keratoplasty, scleral buckle, or to suture an intraocular lens to the iris. The prolene suture also has a greater elasticity and this property may be advantageous in some clinical applications. We feel that a clinical study on humans is now warranted and we have started such a study.
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