This study aimed to investigate the psychological well-being of women who had experienced menopause before the age of 40 years. Participants were women known to the reproductive endocrinology service of a London teaching hospital. They were contacted and invited to participate in the questionnaire study by post. Sixty-four women (41.6%) who completed and returned their questionnaires formed a usable sample. Participants reported high levels of depression and perceived stress, and low levels of self-esteem and life satisfaction, compared to the general population. Self-reports on several dimensions of sexuality were significantly more negative. The following factors could affect the degree of reported distress: age, age at diagnosis, time since diagnosis, already having children, being in a long-term relationship, or having psychological treatment in the past or present. The results suggest that premature menopause could pose significant psychological difficulty for a sizeable proportion of those who have the condition. It is argued that the provision of psychological care should be an integral part of clinical management.
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http://dx.doi.org/10.3109/01674820009075624 | DOI Listing |
JAMA Netw Open
January 2025
Department of Family Medicine, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Republic of Korea.
Importance: There is limited evidence regarding the association between age at menopause and incident type 2 diabetes (T2D).
Objective: To investigate whether age at menopause and premature menopause are associated with T2D incidence in postmenopausal Korean women.
Design, Setting, And Participants: This population-based cohort study was conducted among a nationally representative sample from the Korean National Health Insurance Service database of 1 125 378 postmenopausal women without T2D who enrolled in 2009.
Horm Behav
January 2025
Department of Physical Therapy, School of Health and Social Services, Saitama Prefectural University, Saitama, Japan. Electronic address:
An animal model of 4-vinylcyclohexene diepoxide (VCD)-induced premature ovarian failure was developed to mimic menopause; this model has been used in various field studies. However, detailed reports on the rodent model using VCD are lacking, and the animal species used, administration methods, and hormonal fluctuations in the creation of the VCD model have not been comprehensively elucidated. The aim of this study was to systematically review these aspects of the rodent model using VCD and elucidate its characteristics.
View Article and Find Full Text PDFGinekol Pol
January 2025
Faculty of Medicine, Lazarski University, Warsaw, Poland, Poland.
In women after hematopoietic stem cell transplantation (HSCT), complications associated with the original disease and therapies used both before and after transplantation often occur, which significantly affects their quality of life. The most common gynaecological complications include secondary cancers, premature ovarian insufficiency (POI), infertility and chronic graft-versus-host disease (cGVHD). Cervical cancer is the most common secondary genital cancer in patients after HSCT.
View Article and Find Full Text PDFJACC CardioOncol
December 2024
Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
J Family Med Prim Care
December 2024
Department of Community Medicine and School of Public Health, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Background: Multimorbidity development is linked with the age at menopause. Fewer studies are available to support the findings. This study was conducted to find, how multimorbidity is associated with the natural age of menopause.
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