There are conflicting reports on blood viscosity and its determinants in pre-eclampsia. We investigated the presence of hyperviscosity and its determinants in 25 nulliparous, pre-eclamptic Jamaican women. An equal number of non-pre-eclamptic, gestation-matched women served as controls. There was no statistically significant difference in whole blood, plasma and serum viscosities, as well as in their determinants, namely, haematocrit, fibrinogen, IgM and IgG concentrations between the pre-eclamptic and control groups. This suggests that hyperviscosity is not a feature of pre-eclampsia in this Jamaican population.
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Clin Hemorheol Microcirc
January 2013
Department of Obstetrics and Gynecology, City Hospital of Aschaffenburg, Aschaffenburg, Germany.
Introduction: Previous studies have dealt with maternal blood rheology in preeclampsia (PE), but only a few focused on the fetal rheological parameters in this maternal state. PE is one of the most common severe complications of pregnancy world-wide associated with high maternal morbidity and mortality and intrauterine fetal growth restriction. Our objective was to explore the rheological parameters in the umbilical cord blood at term in the presence of moderate and severe forms of PE.
View Article and Find Full Text PDFZhongguo Zhong Xi Yi Jie He Za Zhi
March 2010
Department of Gynecology & Obstetrics, First Affiliated Hospital, Medical School of Xi'an Jiaotong University, Xi'an 710061.
Objective: To evaluate the efficacy of Salviae injection and ligustrazine injection (S & L) in combining with Western medicine for treatment of early onset of severe pre-eclampsia (EOSP), and its impact on pregnancy.
Methods: An open prospective controlled study was conducted on 63 women suffering from EOSP during the 29th-32th week of pregnancy. They were assigned, according to the sequence of hospitalizing, to the treated group (32 cases) and the control group (31 cases).
Clin Hemorheol Microcirc
August 2005
Department Obstetrics Gynecology, Clinica Obstetric Gynecology, City Hospital, Rüsselsheim, Germany.
Hemorheological parameters were determined in 45 pairs of mothers with severe preeclampsia and their newborns in comparison with 45 women with uncomplicated pregnancies and their newborns. In both groups we investigated red cell deformability, the plasma viscosity, the red cell aggregation (during stasis and low flow), the macromolecules fibrinogen and factor VIIIR:Ag (VWF), and the blood count parameters hemoglobin, hematocrit, white cells, platelets, reticulocytes, MCV, MCHC. Cholesterol and triglycerides were correlated to the parameter of red cell deformability measured as red cell elongation.
View Article and Find Full Text PDFClin Hemorheol Microcirc
October 2004
Department of Basic Medical Sciences (Physiology Section), Faculty of Medical Sciences, The University of the West Indies, Mona Campus, Kingston 7, Jamaica, W.I.
Hyperviscosity of the maternal blood has been reported to be associated with an increased incidence of adverse perinatal outcome in preeclampsia. We related the changes in maternal blood viscosity to perinatal outcome in 47 preeclamptic, nulliparous, black Jamaican women. A group of 49 non-preeclamptic, nulliparous, gestation-matched women acted as controls.
View Article and Find Full Text PDFIndian J Pediatr
August 2003
Department of Transfusion Medicine, The Tamil Nadu Dr. MGR Medical University, Chennai, India.
The dramatic advances that have taken place in recent years in the care of sick and premature infants also have been matched by a similar increase in the use of blood transfusion therapy. Haematological features indicate that a newborn has a blood volume of 85-125 ml/kg the foetal haemoglobin is 60-85% and average Hb in full term infant is 18 gm/dl. By 2-3 months it falls to 11-12 g/dl the main cause of anemia are iron poor diet, weaning diets recurrent or chronic infections and hemolytic episodes in malarious areas.
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