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Technical aspects of neuraxial analgesia during labor and maternity care: an updated overview.
J Anesth Analg Crit Care
January 2025
Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", via Sergio Pansini 5, Naples, 80100, Italy.
Labor analgesia is increasingly widespread throughout the world with a rate ranging from 10 to 60%. The benefits regarding clinical and non-clinical maternal-fetal outcomes are currently discussed in international scientific literature. Even stage of labor needs a different and appropriate approach to control the pain; however, different techniques are reported in literature.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to compare the effectiveness of two sedation combinations—midazolam/meperidine (M/M) vs. midazolam/hydromorphone (M/H)—for pediatric dental patients.
- A review of charts from healthy children aged 2 to 5 who underwent sedation treatment revealed no significant differences in treatment completion, sedation level, or overall effectiveness between the two groups.
- However, the M/H group showed better behavioral scores, suggesting that midazolam and hydromorphone could be a preferable option for moderate sedation in these patients.
Perioperative Analgesic and Sedative Effects of Cannabidiol in Cats Undergoing Ovariohysterectomy.
Animals (Basel)
August 2024
Department of Veterinary Surgery and Animal Reproduction, Faculdade de Medicina Veterinária e Zootecnia, Universidade Estadual Paulista (UNESP), Botucatu 18618-681, Brazil.
The aim of this study was to evaluate the perioperative analgesic and sedative effects of oral CBD in cats undergoing ovariohysterectomy. Twenty-two cats were assigned to receive either oral cannabidiol oil (2 mg/kg, CBD group, = 12) or placebo oil (0.1 mL/kg, Placebo group, = 10) 60 min before the premedication.
View Article and Find Full Text PDFThis non-randomized study aimed to compare the efficacy of two pharmacological treatments, "around-the-clock" analgesic treatment (ACAT) and "on-demand" analgesic treatment (ODAT), for managing postoperative pain following hemorrhoidectomy. Material and The study, conducted from July 2016 to December 2020, included 5335 hemorrhoidectomy patients. Participants were divided into ACAT (3767) and ODAT (1568) groups.
View Article and Find Full Text PDFMeperidine compared to morphine for rigors associated with monoclonal antibody-related infusion reactions.
J Oncol Pharm Pract
June 2024
Department of Pharmacy, University of California at Davis Health System, Sacramento, CA, USA.
Introduction: Infusion reactions, characterized by symptoms such as rigors, fever, and hypotension, are common adverse events that occur during monoclonal antibody (MAB) therapy. The treatment of rigors often involves opioids, most commonly meperidine, despite limited evidence supporting use in the setting of MAB infusions. This study aims to compare the efficacy and safety of intravenous (IV) meperidine and morphine is treatment of MAB-related rigors, filling a significant gap in the literature.
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