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The Use of Autologous Omentum Transposition as a Therapeutic Intervention to Reduce the Complication of Ischemia/Reperfusion Injuries in a Rat Model.
Can J Kidney Health Dis
November 2024
Urology Research Center, Tehran University of Medical Sciences, Iran.
Background: Ischemia/reperfusion injury (IRI) causes cellular dysfunction and death in organs like the kidney, heart, and brain. It involves energy depletion during ischemia and oxidative stress, inflammation, and apoptosis during reperfusion. Kidney IRI often leads to acute kidney injury (AKI) in various clinical scenarios.
View Article and Find Full Text PDFUse of omentum during robotic-assisted reconstructive urological surgery: a systematic review of the current literature.
World J Urol
November 2024
Department of Urology, University of Leipzig, Leipzig, Germany.
Article Synopsis
- - The study reviews the effectiveness of the omentum in robotic-assisted reconstructive urology surgeries, highlighting its biological benefits and potential applications in complex procedures.
- - A systematic search of three databases yielded 13 relevant studies, covering various repairs, such as vesicovaginal and rectourethral fistulas, with recurrence rates between 0% and 6.7% and low complication rates.
- - The authors conclude that using omentum in robotic surgeries could be a safe and efficient option for complicated urological issues, but emphasize the need for more extensive studies to solidify its routine use in the field.
Dear Laparoscopic Surgeons: Caution with the Use of Glutaraldehyde!!!
J Indian Assoc Pediatr Surg
August 2024
Department of Paediatric Surgery, All India Institute of Medical Sciences, New Delhi, India.
Background: The occupational hazards of glutaraldehyde are well known; the possibility of harm to the patients has been highlighted in the form of isolated reports only.
Objective: To synthesize evidence for contact mucosal injury or injury due to intraperitoneal instillation of glutaraldehyde following its use during laparoendoscopy.
Materials And Methods: The current review is Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) compliant.
Intraperitoneal administration of adeno-associated virus encoding microRNA-29b for the treatment of peritoneal metastasis.
Cancer Gene Ther
December 2024
Department of Surgery, Jichi Medical University, Shimotsuke, Japan.
Article Synopsis
- - This study investigates a new method for treating peritoneal metastasis (PM) by using AAV vectors to deliver a tumor-suppressing microRNA, miR-29b, to cells in the peritoneum, which is the lining of the abdominal cavity.
- - The research shows that AAV-DJ serotype effectively boosts miR-29b levels in peritoneal mesothelial cells, leading to reduced tumor cell attachment and decreased fibrosis, especially after a single intraperitoneal injection.
- - Furthermore, the combination of miR-29b delivery with traditional chemotherapy, like paclitaxel, improves treatment outcomes by inhibiting the growth of established PM from gastric and pancreatic cancers.
Vascularized Omentum Lymphatic Transplantation as a Treatment for Chronic Inguinal Ulceration and Lymphedema.
Plast Reconstr Surg Glob Open
August 2024
From the Department of Burns and Cutaneous Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Article Synopsis
- After surgery for tumors, some people have problems with leaking lymphatic fluid and infections in the groin area, making it hard for wounds to heal quickly.
- Doctors used a special method involving a piece of fat (omen) to fill in spaces and help the wounds heal better.
- The procedure worked well for the patient, with no fluid leakage or more wounds, and it helped reduce swelling in the legs.
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