The application of benchmarking techniques to hospital pharmacy practice is discussed. Benchmarking is a process designed to discover best practices through a comparison of various competing methods aimed at achieving a particular goal. Benchmarking antimicrobial drug utilization and rates of bacterial resistance through comparison with a multitude of similar hospitals can be used by an institution both to identify potential problem areas in its pharmacy practice and to aid in establishing appropriate and attainable goals. The effectiveness of various activities targeted at reducing appropriate drug use can also be benchmarked. In 1993, the Benchmarking Program was established at Millard Fillmore Hospital. This program consists of a network of hospital pharmacists who supply data on antimicrobial use, antimicrobial management activities, and rates of antimicrobial resistance. The program was designed both to serve hospital pharmacies in optimizing antimicrobial management and to create a national database for evaluating relationships among antimicrobial use, management, and resistance. Hospitals participating in the Benchmarking Program receive an annual report that allows them to compare themselves with peer groups and with best-performing "benchmark hospitals." All data from U.S. hospitals contained in the Benchmarking Program database are pooled and analyzed to identify meaningful trends. However, information gained from the institutionwide data must be supplemented by studies at the patient level. Benchmarking antimicrobial drug use in an institutional setting can identify successes as well as potential problem areas in pharmacy practice and aid in establishing appropriate and attainable goals.
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http://dx.doi.org/10.1093/ajhp/57.suppl_2.S13 | DOI Listing |
Int J Clin Pharm
January 2025
Department of Clinical Pharmacy, Institute of Pharmacy, Innsbruck University, Innrain 80, 6020, Innsbruck, Austria.
Naunyn Schmiedebergs Arch Pharmacol
January 2025
Department of Pharmacology and Toxicology, School of Pharmacy, University of Health and Allied Sciences, Ho, Ghana.
Purpose: Major depressive disorder is one of the most common and burdensome psychiatric disorders worldwide. This study evaluated the anxiolytic- and antidepressant-like activity of three semi-synthetic derivatives of xylopic acid (XA) to identify the most promising derivative based on mechanism(s) of action, in vivo pharmacokinetics and in vitro cytotoxicity.
Methods: The anxiolytic potential and the involvement of GABAergic mechanisms were assessed in the elevated plus-maze and open field tests in mice.
Nutr Rev
January 2025
Department of Emergency Medicine, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan 64600, China.
Context: Previous studies have explored the relationship between vitamin D and lipid profile in individuals with obesity or overweight women, but the results have been inconsistent.
Objective: This meta-analysis and systematic review of randomized controlled trials (RCTs) was conducted to assess the effect of vitamin D on lipid profile in women who are overweight or obese.
Data Sources: A meticulous search strategy was used across the Scopus, PubMed/Medline, Web of Science, and Embase databases up to June 2024.
J Manag Care Spec Pharm
January 2025
Academy of Managed Care Pharmacy Foundation, Alexandria, VA.
Background: Over the past 5 years, managed care pharmacy has been shaped by a global pandemic, advancements in generative artificial intelligence (AI), Medicare drug price negotiation policies, and significant therapeutic developments. Collective intelligence methods can be used to anticipate future developments in practice to help organizations plan and develop new strategies around those changes.
Objective: To identify emerging trends in managed care pharmacy.
Background: Babesiosis poses significant risks of adverse outcomes in individuals with immunocompromising conditions (IC) and asplenia/hyposplenia (AH). This study compares clinical outcomes between these vulnerable groups and immunocompetent patients.
Methods: A multicenter retrospective cohort study included adult patients with laboratory-confirmed babesiosis from 2009 to 2023.
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