This article includes a description of the uses and indications of liquid injectable silicone and a discussion of the results obtained. Patient selection, indications, mechanism of action, potential complications, and adjunct procedures are also addressed.
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Nat Protoc
January 2025
Department Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany.
Deep and accurate proteome analysis is crucial for understanding cellular processes and disease mechanisms; however, it is challenging to implement in routine settings. In this protocol, we combine a robust chromatographic platform with a high-performance mass spectrometric setup to enable routine yet in-depth proteome coverage for a broad community. This entails tip-based sample preparation and pre-formed gradients (Evosep One) combined with a trapped ion mobility time-of-flight mass spectrometer (timsTOF, Bruker).
View Article and Find Full Text PDFMetab Brain Dis
January 2025
Florey Institute of Neuroscience & Mental Health, Parkville, VIC, Australia.
Substance use disorders (SUDs) pose a significant global health challenge, with relapse being a major obstacle in achieving successful treatment outcomes. In recent years, drug delivery strategies have emerged as promising tools to improve treatment efficacy and patient compliance in the context of SUD. Here we explore a diverse range of drug delivery strategies that have been investigated for addressing relapse behavior in SUD.
View Article and Find Full Text PDFSci Rep
January 2025
Petrochemicals Department, Egyptian Petroleum Research Institute, 1 Ahmed El Zomor St., Nasr City, Cairo, 11727, Egypt.
Recovering the remaining oil after primary and secondary extraction methods poses a significant challenge. Enhanced oil recovery (EOR) techniques, which involve injecting fluids into reservoirs, aim to increase recovery rates. Ionic liquids, known for their adaptability, are emerging as promising agents in EOR, improving oil displacement by reshaping fluid properties and interacting with reservoir rocks.
View Article and Find Full Text PDFBiomed Opt Express
January 2025
Center for Optics, Photonics and Lasers, Department of Physics, Engineering Physics and Optics, Université Laval, 2375 Rue de la Terrasse, Québec, Québec G1V 0A6, Canada.
A miniature electrically tuneable liquid crystal component is used to steer light from -1° to +1° and then to inject into a simple tapered fiber. This allows the generation of various propagation modes, their leakage, and selective illumination of the surrounding medium at different depth levels without using mechanical movements nor deformation. The performance of the device is characterized in a reference fluorescence medium (Rhodamine 6G) as well as in a mouse brain (medullary reticular formation and mesencephalic locomotor regions) during in-vivo experiments as a proof of concept.
View Article and Find Full Text PDFBMC Vet Res
January 2025
Bacterial Diseases of Livestock Research Unit, National Animal Disease Center, Agricultural Research Service, 1920 Dayton Ave, Ames, IA, 50010, USA.
Background: Mycobacterium bovis BCG is the human tuberculosis vaccine and is the oldest vaccine still in use today with over 4 billion people vaccinated since 1921. The BCG vaccine has also been investigated experimentally in cattle and wildlife by various routes including oral and parenteral. Thus far, oral vaccination studies of cattle have involved liquid BCG or liquid BCG incorporated into a lipid matrix.
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