It is expected that any irreducible polynomial with integer coefficients assumes infinitely many prime values provided that it satisfies some obvious local conditions. Moreover, it is expected that the frequency of these primes obeys a simple asymptotic law. This has however been proven for only a few special classes of polynomials. In the most famous unsolved cases the sequence of values is "thin" in the sense that it contains fewer than N(theta) integers up to N for some constant theta < 1. Quite generally it seems to be difficult to show the infinitude of primes in a given thin integer sequence and there is no polynomial for which this has hitherto been done. The polynomial x(2) + y(4) is an example of such a thin sequence; here, specifically, theta = 3/4. We report here the development of new methods that rigorously demonstrate the asymptotic formula in the case of this polynomial and that are applicable to an infinite class of polynomials to which this one belongs. The proof is based partly on a new sieve method that breaks the well-known parity problem of sieve theory and partly on a careful harmonic analysis of the special properties of biquadratic polynomial sequences.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC19742 | PMC |
http://dx.doi.org/10.1073/pnas.94.4.1054 | DOI Listing |
ACS Pharmacol Transl Sci
January 2025
Pharmaceutical Institute, Pharmacology and Toxicology, University of Bonn, Gerhard-Domagk-Str. 3, 53121 Bonn, Germany.
Lipopolysaccharide (LPS)-neutralizing peptides are emerging as new potential therapeutic modalities to treat sepsis and skin infections. Purinergic ligand-gated ion channels (P2X receptors) play a critical role in various biological processes, including inflammation. Recent drug development efforts have significantly focused on the modulation of P2X receptors.
View Article and Find Full Text PDFJ Dent
January 2025
DDS, MS, PhD, Department of Dentistry, Federal University of Rio Grande do Norte, Natal, Brazil. Electronic address:
Objective: To evaluate the influence of different cleaning methods, surface treatments, and aging on the repair bond strength to a CAD/CAM glass-ceramic.
Materials And Methods: Forty-eight lithium disilicate CAD/CAM ceramic blocks were fabricated, sintered, and embedded in acrylic resin. After contamination with human saliva, they were divided according to the factors "Cleaning method" (Control-water/air spray, Air-particle abrasion with AlO, Ivoclean cleaning paste), "Surface treatment" (5% Hydrofluoric acid-HF + Silane, Monobond Etch & Prime-MEP), and "Aging" (thermocycling, no thermocycling).
Commun Phys
January 2025
Accelerator Laboratory, Department of Physics, University of Jyväskylä, Jyväskylä, Finland.
Atomic nuclei serve as prime laboratories for investigations of complex quantum phenomena, where minor nucleon rearrangements cause significant structural changes. Pb is the heaviest known neutron-deficient Pb isotope that can exhibit three distinct shapes: prolate, oblate, and spherical, with nearly degenerate excitation energies. Here we report on the combined results from three state-of-the-art measurements to directly observe these deformations in Pb.
View Article and Find Full Text PDFVet Res Commun
January 2025
ARGO, ICAR- National Dairy Research Institute, Deemed University, Karnal, India.
Sperm motility is the prime functional attribute for semen quality and fertility of the bull. However, the bull's age directly affects the semen quality, and the bull's fertility and productive life decline with age. Even though research on age has been conducted in the past, it is still unclear how old a bull should be maintained at artificial insemination centers.
View Article and Find Full Text PDFFoods
December 2024
Jiangxi Provincial Key Laboratory for Postharvest Storage and Preservation of Fruit and Vegetables, College of Agronomy, Jiangxi Agricultural University, Nanchang 330045, China.
Postharvest quality deterioration is a major factor affecting the economic value and marketing of Nanfeng tangerines. The objective of this study was to explore the effects of luteolin treatment on the postharvest quality and antioxidant capacity of Nanfeng tangerines. We applied 1 g/L and 3 g/L luteolin to fruit after harvest and evaluated the decay rate, postharvest quality, and antioxidant capacity during a 60-day storage period at room temperature.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!