Developmental expression of the estrogen receptor-related receptor gamma in the nervous system during mouse embryogenesis.

Mech Dev

Zentrum für Molekulare Neurobiologie, Institut für Entwicklungsneurobiologie, Universität Hamburg, Martinistrasse 52, D-20246, Hamburg, Germany.

Published: October 2000

The ERR's (estrogen receptor-related receptors) are constitutive activators of the classical estrogen response element. In this report, we demonstrate that ERRgamma is highly expressed in the nervous system of the developing mouse embryo and that the adult pattern of expression of ERRgamma is, with few exceptions, established during embryogenesis. Transcripts are preferentially detected in already differentiating areas of the nervous system.

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http://dx.doi.org/10.1016/s0925-4773(00)00422-6DOI Listing

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