Radical-induced copolymerization of 1-vinyluracil and maleic anhydride gave, after hydrolysis, a polymer containing a 1:1 monomer ratio of 1-vinyluracil-maleic acid. Gamma-Ray-induced copolymerization of 1-vinyluracil with acrylic acid gave a polymer with a ratio of 1:1.7. Similar treatment of 9-vinlyadenine and acrylic acid resulted in a polymer with a 1:3.2 ratio. These three compounds are potent stimulants of poly (uridylic acid) coded polyphenylalanine synthesis in an in vitro cell free system purified from Escherichia coli MRE 600. The double-stranded polymer, poly(inosinic acid)-poly(cytidylic acid), also stimulates polyphenylalanine synthesis in this assay.

Download full-text PDF

Source
http://dx.doi.org/10.1021/bi00693a017DOI Listing

Publication Analysis

Top Keywords

acrylic acid
12
copolymerization 1-vinyluracil
8
acid polymer
8
polyphenylalanine synthesis
8
acid
7
polynucleotide analogs
4
analogs acrylic
4
acid maleic
4
maleic acid
4
acid copolymers
4

Similar Publications

In this study, new cinnamic acid linked to triazole acetamide derivatives was synthesized and evaluated for anti-Alzheimer and anti-melanogenesis activities. The structural elucidation of all analogs was performed using different analytical techniques, including H-NMR, C-NMR, mass spectrometry, and IR spectroscopy. The synthesized compounds were assessed in vitro for their inhibitory activities against acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and tyrosinase enzymes.

View Article and Find Full Text PDF

This work aims to deal with the challenges associated with designing complementary bifunctional electrocatalysts and a separator/membrane that enables rechargeable zinc-air batteries (RZABs) with nearly solid-state operability. This solid-state RZAB was accomplished by integrating a bifunctional electrocatalyst based on Ru-RuO interface nanoparticles supported on nitrogen-doped (N-doped) graphene (Ru-RuO/NGr) and a dual-doped poly(acrylic acid) hydrogel (d-PAA) electrolyte soaked in KOH with sodium stannate additive. The catalyst shows enhanced activity and stability toward the two oxygen reactions, i.

View Article and Find Full Text PDF

Structurally Transformable and Reconfigurable Hydrogel-Based Mechanical Metamaterials and Their Application in Biomedical Stents.

ACS Appl Mater Interfaces

January 2025

Institute of Materials Research and Engineering (IMRE), Agency for Science, Technology and Research (A*STAR), 2 Fusionopolis Way, Innovis #08-03, Singapore 138634, Republic of Singapore.

Mechanical metamaterials exhibit several unusual mechanical properties, such as a negative Poisson's ratio, which impart additional capabilities to materials. Recently, hydrogels have emerged as exceptional candidates for fabricating mechanical metamaterials that offer enhanced functionality and expanded applications due to their unique responsive characteristics. However, the adaptability of these metamaterials remains constrained and underutilized, as they lack integration of the hydrogels' soft and responsive characteristics with the metamaterial design.

View Article and Find Full Text PDF

Microgel-Guided MXene Assembly for High-Performance, Low-Solid Content Conductive Inks.

ACS Appl Mater Interfaces

January 2025

Department of Chemical Engineering, University of South Carolina, Columbia, South Carolina 29208, United States.

Rapid evolution of smart devices necessitates high-performance, lightweight materials for effective electromagnetic interference (EMI) shielding. TiCT MXene nanosheets are promising for such applications, yet the high solid content typically required for 3D-printable MXene inks limits their scalability and cost efficiency. In this study, we present an MXene-based ink with an ultralow solid content (0.

View Article and Find Full Text PDF
Article Synopsis
  • Smart hydrogel sensors can respond to stimuli like pH and temperature, with potential uses in biomedical, environmental, and wearable tech.
  • Developing wearable hydrogels that respond to body temperature, adhere well, and are transparent has been challenging.
  • The newly created thermo-responsive hydrogel changes properties based on temperature, is made using 3D printing, and can detect temperature and strain, making it ideal for smart medical applications.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!