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Prevalence and patient characteristics associated with cardiovascular disease risk factor screening in UK primary care for people with severe mental illness: an electronic healthcare record study.
BMJ Ment Health
January 2025
Division of Psychiatry, University College London, London, UK.
Background: People with severe mental illness (SMI) are at increased risk of cardiovascular disease (CVD), and initiatives for CVD risk factor screening in the UK have not reduced disparities.
Objectives: To describe the annual screening prevalence for CVD risk factors in people with SMI from April 2000 to March 2018, and to identify factors associated with receiving no screening and regular screening.
Methods: We identified adults with a diagnosis of SMI (schizophrenia, bipolar disorder or 'other psychosis') from UK primary care records in Clinical Practice Research Datalink.
A systematic review of reports on aquatic envenomation: are there global hot spots and vulnerable populations?
J Venom Anim Toxins Incl Trop Dis
December 2024
Department of Tropical Medicine, Medical Microbiology and Pharmacology, John A. Burns School of Medicine, University of Hawai'i at Mānoa, Honolulu, Hawaii, United States.
Envenomation by aquatic species is an under-investigated source of human morbidity and mortality. Increasing population density along marine and freshwater coastlines increases these incidents. Specific occupational groups - including commercial fishery workers, fisherfolk, marine tourism workers, and researchers - rely on aquatic resources for their livelihood.
View Article and Find Full Text PDFA Critical Appraisal of the Application of Frailty and Sarcopenia in the Spinal Oncology Population.
Global Spine J
January 2025
Spine Surgery Program, Department of Surgery, McGill University, Montreal, QC, Canada.
Study Design: Systematic review and clinimetric analysis.
Objectives: Frailty and sarcopenia predict worse surgical outcomes among spinal degenerative and deformity-related populations; this association is less clear in the context of spinal oncology. Here, we sought to identify frailty and sarcopenia tools applied in spinal oncology and appraise their clinimetric properties.
PD-L1-Expression in in primary and recurrent vulvar squamous cell cancer.
Gynecol Oncol
January 2025
Institute of Pathology, Erlangen University Hospital, Comprehensive Cancer Center Erlangen-European Metropolitan Area of Nuremberg (CCC ER-EMN), Friedrich-Alexander-Universität Erlangen-Nürnberg, Krankenhausstrasse 8-10, 91054 Erlangen, Germany.
Background: Squamous cell vulvar carcinoma is a rare malignant disease of women. In higher tumor stages survival rates are poor. Therapy options are limited.
View Article and Find Full Text PDFDeep Brain Stimulation (DBS) and Motor Cortex Stimulation (MCS) for Central Post-Stroke Pain: A Systematic Review And Meta-Analysis.
Pain Med
January 2025
Oxford Functional Neurosurgery Group, John Radcliffe Hospital, Oxford, United Kingdom.
Article Synopsis
- Deep Brain Stimulation (DBS) and Motor Cortex Stimulation (MCS) are invasive therapies used to treat neuropathic pain like Central Post-Stroke Pain, but there's been no thorough comparison of their effectiveness using standardized pain metrics.
- A systematic review and meta-analysis were conducted, reviewing 32 studies (330 patients) and measuring pain relief through VAS and NRS scores, finding that MCS had a slightly better improvement rate compared to DBS.
- Despite showing MCS as potentially more effective, further studies are needed to establish the best surgical approach for treating Central Post-Stroke Pain.
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