The employment of periodate oxidation in the chemistry of nucleic acids and their components is reviewed. The reaction mechanism, structural requirements to substrates, and synthesis of dialdehyde derivatives of nucleosides, nucleotides, and oligonucleotides are discussed in the first part. The second part involves chemical, physicochemical, and biological properties of the dialdehyde derivatives, as well as their use for the affinity modifications of proteins.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
dialdehyde derivatives
12
oxidation chemistry
8
chemistry nucleic
8
derivatives nucleosides
8
nucleosides nucleotides
8
[periodate oxidation
4
nucleic acid
4
acid dialdehyde
4
nucleotides oligonucleotides]
4
oligonucleotides] employment
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!