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CHOLANGIOCARCINOMA: EPIDEMIOLOGY, HISTOPATHOLOGY, AND POTENTIAL PROGNOSTIC AND THERAPEUTIC IMPLICATIONS IN A COHORT FROM A REFERENCE CENTER IN SOUTHERN BRAZIL.
Arq Bras Cir Dig
January 2025
Santa Casa de Misericórdia de Porto Alegre - Porto Alegre (RS), Brazil.
Background: Cholangiocarcinoma (CCA) is a rare neoplasm, with high mortality, originating in the bile ducts. Its incidence is higher in Eastern countries due to the endemic prevalence of liver parasites. Factors such as metabolic syndrome, smoking, and pro-inflammatory conditions are also linked to the disease.
View Article and Find Full Text PDFTrends of alkaline phosphatase to prealbumin ratio in patients with hepatitis B linked to hepatocellular carcinoma development.
World J Gastroenterol
January 2025
Department of Epidemiology and Health Statistics, Dalian Medical University, Dalian 116044, Liaoning Province, China.
Background: Chronic hepatitis B often progresses silently toward hepatocellular carcinoma (HCC), a leading cause of mortality worldwide. Early detection of HCC is crucial, yet challenging.
Aim: To investigate the role of dynamic changes in alkaline phosphatase to prealbumin ratio (APR) in hepatitis B progression to HCC.
Risks of parasitic helminth disease outbreaks and influence of physico-chemical factors in flood prone areas of Yaoundé, Cameroon.
Parasite Epidemiol Control
February 2025
Centre for Research on Health and Priority Pathologies, Institute of Medical Research and Medicinal Plants Studies, PO box 13033 Yaoundé, Cameroon.
Background: Urbanization coupled with poverty has promoted the exploitation of risk zones like flood-prone areas in the city of Yaoundé. The overcrowding and poor hygiene observed in these areas are responsible for the unsmiling variations in environmental cleanliness, exploitation of river water for domestic purposes thus putting them at risk for parasitic disease transmissions. This study was conducted in order to assess the risks of human helminthiases outbreaks in relation to water physico-chemical factors in the city of Yaoundé.
View Article and Find Full Text PDFAssociation between risk of ischemic stroke and liver enzymes levels: a systematic review and meta-analysis.
BMC Neurol
January 2025
Faculty of Medicine, MUST University, Giza, Egypt.
Background: Ischemic stroke is a major public health concern, contributing significantly to global morbidity and mortality. Recent studies have suggested that alterations in liver enzymes may be linked to the risk of developing a stroke. However, the relationship between liver enzymes and ischemic stroke remains unclear.
View Article and Find Full Text PDFHealth risk assessment via ingestion of disinfection by-products in drinking water.
Sci Rep
January 2025
Department of Health Hazards Surveillance, Hangzhou Center for Disease Control and Prevention (Hangzhou Health Supervision Institution), Hangzhou, 310021, China.
Disinfection is a critical process to ensure the safety of drinking water. To curb the spread of various bacteria and viruses, disinfectants are extensively employed in communities, hospitals, sewage treatment plants, and other settings. However, disinfectants can produce disinfection by-products (DBPs) that threaten human health.
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