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Article Synopsis
  • Botryomycosis is a rare bacterial infection that mimics mycetoma and can affect both immunocompromised and immunocompetent individuals, commonly presenting as a chronic granulomatous infection with sulfur granules.
  • An 8-year-old boy with a 4-mm subcutaneous tumor on his heel was diagnosed with botryomycosis after surgical removal and histopathological analysis revealed Gram-positive cocci and the Splendore-Hoeppli phenomenon.
  • The patient was treated effectively with surgical excision and antibiotics, and the case highlights the importance of early detection and investigation of small lesions to prevent more severe infections.
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Botryomycosis is a rare chronic suppurative bacterial infection of skin and viscera mostly reported in immunocompromised adults. Most of published literature on botryomycosis are case reports. Though morphological presentation of cutaneous botryomycosis has been described as nodules, sinus, abscesses, and ulcers discharging seropurulent exudates, sequential evolution of lesions is not clear.

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Botryomycosis.

Clin Dermatol

October 2012

Mycology Section, Centro Dermatológico Dr. Ladislao de la Pascua, Mexico, DF, Mexico.

Botryomycosis is a chronic, granulomatous, infectious disease caused by several genera of bacteria with the formation of grains. The factors involved in its development are low virulence, an intermediate inoculum, and the immunologic status of the host. The pathogenesis of the disease is not well established, but the Splendore-Hoeppli phenomenon, which explains the formation of grains and the antigen-antibody reaction that characterizes the disease, is involved.

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[Staphylococcus aureus isolated from a case of lymph node botryomycosis].

Arch Pediatr

September 2008

Service d'anatomie pathologique et de neuropathologie, CHU de la Timone, Marseille cedex 05, France.

Botryomycosis is an uncommon chronic bacterial infection, which usually involves the skin and the subcutaneous tissues. Visceral involvement often occurs in immunodepressed patients. We describe the case of a 4-year-old boy who presented a right inguinal inflammatory mass associated with pruritic papules without fever.

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