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Clinical and Pathological Characteristics of Chronic Otomastoiditis: A Retrospective Analysis of Risk Factors, Outcomes, and Antibiotic Resistance Patterns.
Healthcare (Basel)
December 2024
Department of Mother and Baby, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Chronic otomastoiditis is a complex inflammatory condition frequently associated with delayed diagnosis, inadequate antibiotic use, and healthcare disparities. This study aimed to analyze the clinical, demographic, and microbiological characteristics of chronic otomastoiditis and its complications over a 10-year period in rural versus urban populations. This retrospective study included 292 patients with chronic otomastoiditis admitted to the ENT Clinic of Craiova County Emergency Clinical Hospital from 2013 to 2023.
View Article and Find Full Text PDFBacteriological profile, antibiotic susceptibility, and biofilm formation in children with chronic suppurative otitis media.
Int J Pediatr Otorhinolaryngol
December 2024
Medical Research Center, Hawler Medical University, Erbil, Iraq. Electronic address:
Background: Chronic suppurative otitis media is predominantly caused by aerobic bacterial infections, complicated by antibiotic-resistant strains and biofilm formation. This study aims to identify the aerobic bacterial pathogens in chronic suppurative otitis media among children and assess their antibiotic susceptibility patterns. The potential link between biofilm formation and antibiotic resistance is also evaluated.
View Article and Find Full Text PDFAcute mastoiditis: 30 years review in a tertiary hospital.
Int J Pediatr Otorhinolaryngol
December 2024
Department of Otolaryngology, Marqués de Valdecilla University Hospital, Santander, Spain; Institute of Research Valdecilla (IDIVAL), Santander, Spain; Department of Medical and Surgical Sciences, University of Cantabria, Santander, Spain.
Objective: Acute mastoiditis, the most common complication of acute otitis media, is approached in our study, focused on children from the Autonomous Community of Cantabria, Spain. The aim is to analyze its clinical-epidemiological characteristics and propose diagnostic and treatment recommendations.
Study Design/setting: We conducted a 30-year retrospective study on patients under 18 years of age diagnosed with acute mastoiditis in Cantabria.
Small Children Receive Large Doses, While Large Children Receive Low Doses of Amoxicillin Per kg.
Clin Pediatr (Phila)
November 2024
Kapi'olani Medical Center For Women & Children, Honolulu, HI, USA.
Purpose: With increasing pneumococcal penicillin resistance, physicians treat pneumococcal infections with high-dose amoxicillin (80-90 mg/kg/d). High-dose amoxicillin approaches adult doses which makes clinicians reluctant to exceed "adult doses." This study examines the disparity of amoxicillin dosing between the ages of children.
View Article and Find Full Text PDFAsymptomatic nasopharyngeal carriage of multidrug resistant bacteria among children at University of Gondar Hospital Northwest Ethiopia Revealing Hidden Health Risks.
Sci Rep
November 2024
Department of Medical Microbiology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Gram-negative bacteria in the nasopharynx can eventually invade bacteria-limited sites and cause serious illnesses such as meningitis, otitis media, and pneumonia. However, data related to the carriage of these bacteria in children attending outpatient departments in the study area are limited. To assess nasopharyngeal carriage, antibiotic susceptibility patterns, and associated factors of gram-negative bacteria among children attending the outpatient department at the University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia.
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