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Mpox and Lessons Learned in the Light of the Recent Outbreak: A Narrative Review.
Viruses
October 2024
Fourth Department of Internal Medicine, Attikon University Hospital, School of Medicine, National and Kapodistrian University of Athens, 12462 Athens, Greece.
According to the WHO, more than 90,000 cases of mpox have been reported since the 2022 worldwide outbreak, which resulted in 167 deaths, while a new outbreak in Africa since 2023 has resulted in over 18,000 cases and 617 deaths. Mpox is a zoonosis caused by the monkeypox virus, a double-stranded DNA virus belonging to the Orthopoxvirus genus, which causes smallpox-like illness. Until 2022, cases were predominately located in West and Central Africa, with only sporadic cases and outbreaks reported in other parts of the world.
View Article and Find Full Text PDFEffectiveness of a single dose of JYNNEOS vaccine in real world: A systematic review and meta-analysis.
Health Sci Rep
September 2024
Escuela de Medicina Universidad César Vallej Trujillo Peru.
Background: Mpox infection is a zoonotic illness that resembles smallpox. Vaccination is widely regarded as a vital effective method of preventing mpox, however, there is lack of consensus of effectiveness of a single dose of mpox vaccine in the current 2022-2023 outbreak. We pooled data from real-world studies to evaluate the efficacy of the JYNNEOS vaccination given as a single dosage.
View Article and Find Full Text PDFArticle Synopsis
- Monkeypox (Mpox) is an Orthopoxvirus causing skin blisters with a mortality rate of 0-10% and has seen an increase in cases since the end of global smallpox vaccinations.
- This review discusses updates on Mpox's transmission, symptoms, diagnosis, prevention, and treatment, highlighting the role of AI in predicting the disease.
- Key prevention strategies involve PCR testing for early detection, vaccination with JYNNEOS and ACAM2000, and minimizing contact with symptomatic individuals, similar to STI prevention practices.
The spread of the coronavirus SARS-CoV-2 has stimulated eschatological speculation. To the environmentalist and liberal diagnostician that had already been warning about the Anthropocene and the breakdown of post-Cold War global harmony, an alarm has now been added that in its worst prognosis estimates that, in 2020, we only started witnessing the beginning of a staggered health debacle. The idea of the world, as conceptual support for an imaginary community with global reach, has become a crisis.
View Article and Find Full Text PDFHuman monkeypox virus: Epidemiologic review and research progress in diagnosis and treatment.
J Clin Virol
April 2024
Department of Clinical Laboratory, National Clinical Research Center for Child Health, National Children's Regional Medical Center, Children's Hospital, Zhejiang University School of Medicine, Hangzhou 310052, China. Electronic address:
Monkeypox virus (MPXV) is responsible for causing a zoonotic disease called monkeypox (mpox), which sporadically infects humans in West and Central Africa. It first infected humans in 1970 and, along with the variola virus, belongs to the genus Orthopoxvirus in the poxvirus family. Since the World Health Organization declared the MPXV outbreak a "Public Health Emergency of International Concern" on July 23, 2022, the number of infected patients has increased dramatically.
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