[Mooren ulcer].

J Fr Ophtalmol

Service d'Ophtalmologie, Hôpital Saint-Antoine, assistance publique des Hôpitaux de Paris, France.

Published: September 2000

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Atypical conjunctival sporotrichosis secondary to Mooren's ulcer: a case report.

BMC Infect Dis

January 2025

Liaoning Provincial Key Laboratory of Cornea and Ocular Surface Diseases, Liaoning Provincial Optometry Technology Engineering Research Center, The Third People's Hospital of Dalian, Dalian Municipal Eye Hospital, Dalian Municipal Cancer Hospital, No. 40, Qianshan Road, Ganjingzi District, Dalian, Liaoning, China.

Background: Conjunctival sporotrichosis is a rare fungal infection, typically presenting as granulomatous lesions. Its manifestations can be atypical, particularly in immunosuppressed patients. Here, we present a rare case of a Mooren's ulcer patient with bulbar conjunctival Sporotrichosis presenting as a salmon-pink tumor.

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November 2024

Xiamen Eye Center and Eye Institute of Xiamen University, School of Medicine, Xiamen, China.

Purpose: The purpose of this study was to investigate the clinical characteristics of patients with corneal Mooren's ulcers (MU) and explore potential risk factors for recurrence after keratoplasty.

Methods: The study retrospectively analyzed 87 patients (101 eyes) diagnosed with MU. Factors associated with recurrence after keratoplasty were identified using correlation analysis, and a clinical scoring system was developed based on the magnitude of the univariate and multivariate logistic regression analysis.

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Mooren's ulcer is a painless and idiopathic ulcer of the peripheral cornea related to autoimmunity against a corneal stromal antigen, calgranulin C. Corneal involvement is isolated. There are no specific histopathological features to differentiate Mooren's ulcer from pseudo-Mooren's, the latter being part of a systemic disease.

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Article Synopsis
  • Mooren's ulcer (MU) is a rare and serious eye condition that causes crescent-shaped corneal ulcers, which can lead to blindness if untreated.
  • Despite various treatments available, there is no definitive evidence on the best approach due to a lack of thorough clinical trials.
  • A case study of a 20-year-old male who underwent a personalized treatment plan using corticosteroids, surgery, and Cyclosporine A showed successful healing of the ulcer and no disease recurrence, with AS-OCT imaging helping to guide the treatment effectively.
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