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The efficacy and safety of suvemcitug, envafolimab, and FOLFIRI in microsatellite-stable or mismatch repair-proficient colorectal cancer: preliminary results of a phase 2 study.
Int J Colorectal Dis
January 2025
Internal Medicine, Jilin Cancer Hospital, Changchun, China.
Purpose: This phase II study is designed to evaluate the combination therapy involving suvemcitug and envafolimab with FOLFIRI in microsatellite-stable or mismatch repair-proficient (MSS/pMMR) colorectal cancer (CRC) in the second-line treatment setting.
Methods: This study is a non-randomized, open-label prospective study comprising multiple cohorts (NCT05148195). Here, we only report the data from the CRC cohort.
Areas for action to promote positive forms of masculinities in preventing violence against women: a concept mapping study in Spain.
Int J Equity Health
January 2025
Department of Community Nursing, Preventive Medicine and Public Health and History of Science, University of Alicante, Alicante, Spain.
Background: Violence against women (VAW) perpetrated by men is a public health problem of significant magnitude that negatively affects the whole society. Unequal gender relations produce differentiated positions in the social structure; gender roles that position men and women differently are defined and which are at the root of VAW. Framed within the European PositivMasc project, the aim of this study was to identify the areas for action to promote positive masculinities in preventing VAW in Spain, based on community stakeholders' perceptions on their importance and applicability.
View Article and Find Full Text PDFMedical students' attitudes toward AI in education: perception, effectiveness, and its credibility.
BMC Med Educ
January 2025
NUST School of Health Sciences, National University of Sciences and Technology (NUST), Sector, Islamabad, H-12, 44000, Pakistan.
Background: The rapid advancement of artificial intelligence (AI) has revolutionized both medical education and healthcare by delivering innovative tools that enhance learning and improve overall outcomes. The study aimed to assess students' perceptions regarding the credibility and effectiveness of AI as a learning tool and to explore the dynamics of integrating AI in medical education.
Methodology: A cross-sectional study was carried out across medical colleges in Pakistan.
Experience and role of Italian nurses working in genetic clinics: a descriptive phenomenological qualitative study.
BMC Nurs
January 2025
Medical Genetics Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Background: In several countries, the role of the genetic nurse has developed over decades, becoming well-recognized and integrated into healthcare systems. In contrast, in Italy, this role is still emerging, with no formal legal recognition and limited awareness among healthcare professionals and hospital administrators. Given this context, it is crucial to assess how the role and activities of nurses in genetic clinics in Italy are perceived.
View Article and Find Full Text PDFThe intermediary effect of work stress on the relationship between off-duty professional growth and reflective ability among mid- and senior-level nurses.
BMC Nurs
January 2025
School of Nursing, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Background: Mid- to senior-level nurses play a pivotal role in healthcare. Their reflective ability is crucial for clinical decision-making and the continuous improvement of nursing practices. Although numerous studies have emphasized the importance of enhancing reflective ability among mid- to senior-level nurses, the specific relationship between off-duty professional growth, dual work stress, and reflective ability remains unclear.
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