Using data from Aging and Health Dynamics (AHEAD), this research investigated a model predicting an older adult's assessment regarding the chances (from 0 to 100) of leaving a financial bequest. Structural equation modeling analyses revealed three significant predictors of a high assessment (i.e., older age, high sense of control, and high socioeconomic status) and three predictors of a low assessment (i.e., race, physical health problems, and assessment of the chances of medical expenses depleting savings). Whites had higher financial bequests assessments than non-Whites. Physical health problems and the depleting savings assessment exerted negative effects on the financial bequest assessment. Marital status and negative psychological functioning exerted indirect effects through sense of control and through the depleting savings assessment.
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http://dx.doi.org/10.2190/AJJ3-AVG7-QKMW-R21R | DOI Listing |
J Proteome Res
January 2025
Departamento de Bioquímica, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo 04023-901, Brazil.
Antivenoms are the only effective treatment for snakebite envenomation and have saved countless lives over more than a century. Despite their value, antivenoms present risks of adverse reactions. Current formulations contain a fraction of nonspecific antibodies and serum proteins.
View Article and Find Full Text PDFStructure
January 2025
Structural Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA. Electronic address:
Within the course of evolution, TIR (Toll/interleukin-1 receptor) domains acquired a myriad of functional specificities. This has significantly added to their well-established roles in innate immune signaling. These additional functions include nicotinamide adenine dinucleotide (NAD)(P) hydrolase, RNA/DNA nuclease (in plants), CN (cyclic nucleotide) cyclase, and base exchanger activities.
View Article and Find Full Text PDFHeliyon
January 2025
Water Resources Research Center, Arba Minch Water Technology Institute, Arba Minch University, Arba Minch, Ethiopia.
This study investigates the integrative effects of irrigation water management allowable depletion (MAD), furrow irrigation methods (FIM), and nitrogen fertilizer application rate (NFAR) on tomato yield components. These yield components include marketable, unmarketable, and total yield. Additionally, the study examines crop agronomy components such as plant height, number of branches, and root depth in semi-arid Southern Ethiopia.
View Article and Find Full Text PDFScientificWorldJournal
January 2025
Department of Forestry and Climate Change, Injibara University, Injbara, Ethiopia.
was first introduced to Ethiopia in the late 19 century to address the scarcity of firewood and construction wood in the capital city. Since then, it has spread across the country and has become an important source of income for many households while also reducing the need for deforestation. Despite concerns raised by environmentalists about its eco-hydrological impact, the plantation has expanded to cover a vast area of the nation, including farmlands and mountainous regions.
View Article and Find Full Text PDFMol Ther Oncol
September 2024
Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Hematopoietic stem cell transplantation (HSCT) is widely used to treat patients with life-threatening hematologic and immune system disorders. Current nontargeted chemo-/radiotherapy conditioning regimens cause tissue injury and induce an array of immediate and delayed adverse effects, limiting the application of this life-saving treatment. The growing demand to replace canonical conditioning regimens has led to the development of alternative approaches, such as antibody-drug conjugates, naked antibodies, and CAR T cells.
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