A new, stereocontrolled approach to iminosugar C-glycosides from L-sorbose.

Org Lett

Institut de Chimie Organique et Analytique, Faculté des Sciences, BP 6759, 45067 Orléans Cedex 2, France.

Published: September 2000

The efficient synthesis of the iminoalditols derivatives 1 and 2 (nojirimycin alpha-C-glycosides) has been achieved in 10 steps from commercially available 2,3;4,6-di-O-isopropylidene-alpha-L-sorbofuranose in an overall yield of 23-27%.

Download full-text PDF

Source
http://dx.doi.org/10.1021/ol0062493DOI Listing

Publication Analysis

Top Keywords

stereocontrolled approach
4
approach iminosugar
4
iminosugar c-glycosides
4
c-glycosides l-sorbose
4
l-sorbose efficient
4
efficient synthesis
4
synthesis iminoalditols
4
iminoalditols derivatives
4
derivatives nojirimycin
4
nojirimycin alpha-c-glycosides
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!