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Severe ergot-induced lower limb ischaemia treated by epidural local anaesthetic.
Eur J Vasc Endovasc Surg
September 2000
Department of Vascular Surgery, Rambam Medical Center and The Bruce Rappaport Faculty of Medicine, Haifa, Israel.
Ergot induced peripheral vascular insufficiency, non-interventional treatment.
Cathet Cardiovasc Diagn
March 1994
Department of Medicine, Loyola University Medical Center, Maywood 60153.
We report a case of ergotamine tartrate induced severe vasospasm in the renal arteries and the arteries of the lower extremities. Classic features seen on peripheral angiography make the diagnosis. Anticoagulation, thrombolysis, vasodilation, steroids, and prostaglandin inhibitors all have been successfully used to treat symptomatic ergot induced arterial vasospasm.
View Article and Find Full Text PDFCoordinate induction and activation of metalloproteinase and ascorbate depletion in structural luteolysis.
Endocrinology
August 1993
Department of Obstetrics/Gynecology, Yale University School of Medicine, New Haven, Connecticut 06510-8063.
Structural luteolysis was found decades ago to be induced by PRL in the hypophysectomized rat, but the mechanisms of this process are unknown. To gain information on mechanisms of luteal involution, we developed an animal model that circumvented complex surgery and provided ample tissue for analyses. Gonadotropin-synchronized ovulation and luteinization were induced in immature rats, followed by treatment with ergot alkaloid and PRL.
View Article and Find Full Text PDFBilateral upper extremity ischemia after administration of dihydroergotamine-heparin for prophylaxis of deep venous thrombosis.
J Vasc Surg
October 1988
Department of Surgery, University of South Florida, Tampa.
Prolonged arterial spasm as a complication of ergot-containing medications has been reported since antiquity. This article describes our experience with a patient who had severe bilateral arterial spasm in the upper extremities 6 days after the initiation of a regimen of dihydroergotamine and heparin for prophylaxis against deep venous thrombosis. The spasm was refractory to oral calcium channel blocking agents and direct intraarterial infusion of tolazoline (Priscoline).
View Article and Find Full Text PDFErgot-induced vasospasm of the lower extremities treated with epidural anaesthesia.
Scand J Thorac Cardiovasc Surg
March 1976
No reliable treatment to reverse severe ergot-induced vasopasm is available. A case of ergotamine-induced vasospasm of the lower extremities is presented. A combined treatment of vasodilators, infusion of low molecular dextran and high epidural anaesthesia apparently prevented extremity gangrene from occurring.
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