Prevalence of Müllerian duct anomalies detected at ultrasound.

Am J Med Genet

Center VI, Diagnostic Imaging and Radiology, Children's National Medical Center, George Washington University Medical Center, Washington, District of Columbia, USA.

Published: September 2000

The true prevalence of müllerian duct abnormalities is not well established. We used standard ultrasound examinations to establish the prevalence of müllerian duct abnormalities in girls and women who were evaluated for reasons unrelated to the presence of uterine anomalies. Prospective ultrasound examinations for nonobstetric indications in 2,065 consecutive girls and women (aged 8-93) showed that 8 had anomalies, including bicornuate uterus, septate uterus, and double uterus. In this first attempt to determine the prevalence of uterine anomalies in the general population, using noninvasive methodology, the rate of anomalies was 3.87 per 1,000 women (exact 95% confidence interval: 1.67-7.62), or approximately 1 in 250 women. This prevalence estimate may be greater than the true rate if selection biases are strong, or less than the true prevalence if ultrasound detection rates are low. As a first attempt to establish the prevalence by pelvic ultrasound in a consecutive series, these data may serve as a baseline estimate.

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http://dx.doi.org/10.1002/1096-8628(20000904)94:1<9::aid-ajmg3>3.0.co;2-hDOI Listing

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